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All Studies   Meta Analysis       

An Effective Treatment for Coronavirus (COVID-19)

Todaro et al.
Mar 2020  
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HCQ for COVID-19
1st treatment shown to reduce risk in March 2020, now with p < 0.00000000001 from 419 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19hcq.org
Discussion of existing research, treatment guidelines, and mechanisms of action for CQ and HCQ, recommending use.
Reviews covering hydroxychloroquine for COVID-19 include1-26.
Todaro et al., 13 Mar 2020, preprint, 2 authors.
This PaperHCQAll
An Effective Treatment for Coronavirus (COVID-19)
MD (Columbia MD James M Todaro, Gregory J Rigano, Cln
doi:10.1016/S1473-3099(03)00806-5.4
Recent guidelines from South Korea and China report that chloroquine is an effective antiviral therapeutic treatment against Coronavirus Disease 2019. Use of chloroquine (tablets) is showing favorable outcomes in humans infected with Coronavirus including faster time to recovery and shorter hospital stay. US CDC research shows that chloroquine also has strong potential as a prophylactic (preventative) measure against coronavirus in the lab, while we wait for a vaccine to be developed. Chloroquine is an inexpensive, globally available drug that has been in widespread human use since 1945 against malaria, autoimmune and various other conditions.
License Due to urgency, certain parts of this publication are taken directly from their attributed source. Cite them accordingly. In all other circumstances, the GNU General Public License v3.0 applies. Disclaimer This white paper is for information purposes only. The authors and or its affiliates does not guarantee the accuracy of or the conclusions reached in this white paper, and this white paper is provided "as is". The authors and or its affiliates not make and expressly disclaims all representations and warranties, express, implied, statutory or otherwise, whatsoever, including, but not limited to: (i) warranties of merchantability, fitness for a particular purpose, suitability, usage, title or noninfringement; (ii) that the contents of this white paper are free from error; and (iii) that such contents will not infringe third-party rights. The authors and or its affiliates shall have no liability for damages of any kind arising out of the use, reference to, or reliance on this white paper or any of the content contained herein, even if advised of the possibility of such damages. In no event will the authors and or its affiliates be liable to any person or entity for any damages, losses, liabilities, costs or expenses of any kind, whether direct or indirect, consequential, compensatory, incidental, actual, exemplary, punitive or special for the use of, reference to, or reliance on this white paper or any of the content contained herein, including, without..
References
Kono, Tatsumi, Imai, Inhibition of human coronavirus 229E infection in human epithelial lung cells (L132) by chloroquine: involvement of p38 MAPK and ERK, J
Martínez, martinez-aceves@yale
Raoult, Chloroquine and hydroxychloroquine as available weapons to fight COVID-19, International Journal of Antimicrobial Agents Available online
Rodrigo, Luiza, Paula, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models, J
Zhang, Yi, Li, Chloroquine inhibits the endosomal Viral an RNA Release and autophagy in-dependent Viral Replication and Effectively Prevents CARE OF to Fetal Transmission of Zika Virus, J] Antiviral Res, doi:10.1016/j.antiviral.2019.104547
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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