An Effective Treatment for Coronavirus (COVID-19)
Todaro and Rigano (Review) (Preprint)
Todaro, An Effective Treatment for Coronavirus (COVID-19), and Rigano (Review) (Preprint)
Discussion of existing research, treatment guidelines, and mechanisms of action for CQ and HCQ, recommending use.
Todaro et al., 13 Mar 2020, preprint, 2 authors.
Abstract: An Effective Treatment for Coronavirus
(COVID-19)
Presented by: James M. Todaro, MD (Columbia MD, jtodaro2@gmail.com)
and Gregory J. Rigano, Esq. (grigano1@jhu.edu)
In consultation with Stanford University School of Medicine, UAB
School of Medicine and National Academy of Sciences researchers.
March 13, 2020
Translation in Spanish and Italian at end of document.
translations coming.
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Summary
Recent guidelines from South Korea and China report that chloroquine
is an effective antiviral therapeutic treatment against Coronavirus
Disease 2019. Use of chloroquine (tablets) is showing favorable
outcomes in humans infected with Coronavirus including faster time to
recovery and shorter hospital stay. US CDC research shows that
chloroquine also has strong potential as a prophylactic (preventative)
measure against coronavirus in the lab, while we wait for a vaccine to
be developed. Chloroquine is an inexpensive, globally available drug
that has been in widespread human use since 1945 against malaria,
autoimmune and various other conditions.
Chloroquine: C18H26ClN3
Background
The U.S. CDC and World Health Organization have not published
treatment measures against Coronavirus disease 2019 (“COVID-19”).
Medical centers are starting to have issues with traditional
protocols. Treatments, and ideally a preventative measure, are
Informational Purposes Only
1
needed.
South Korea and China have had significantly more exposure
and time to analyze diagnostic, treatment and preventative options.
The U.S., Europe and the rest of the world can learn from their
experience. According to former FDA commissioner, board member of
Pfizer and Illumina, Scott Gotlieb MD, the world can learn the most
about COVID-19 by paying closest attention to the response of
countries that have had significant exposure to COVID-19 before the
U.S. and Europe.1
As per the U.S. CDC, “Chloroquine (also known as chloroquine
phosphate) is an antimalarial medicine… Chloroquine is available in
the United States by prescription only… Chloroquine can be prescribed
for either prevention or treatment of malaria. Chloroquine can be
prescribed to adults and children of all ages. It can also be safely
taken by pregnant women and nursing mothers.”2
CDC research also shows that “chloroquine can affect virus infection
in many ways, and the antiviral effect depends in part on the extent
to which the virus utilizes endosomes for entry. Chloroquine has been
widely used to treat human diseases, such as malaria, amoebiosis, HIV,
and autoimmune diseases, without significant detrimental side
effects.”3
The treatment guidelines of both South Korea and China against COVID19 are generally consistent, outlining chloroquine as an effective
treatment.
Specifically, according to the Korea Biomedical Review, in February
2020 in South Korea, the COVID-19 Central Clinical Task Force,
composed of physicians and experts treating patients agreed upon
treatment principles for patients with COVID-19.4 In China, the
General Office of the National Health Commission, General Office of
the State Administration of Traditional Chinese Medicine as well as a
Multi-Center Collaborative Group of Guangdong Provincial Department of
Science and Technology and Guangdong Provincial Health Comp and the
1
https://www.cnbc.com/video/2020/03/02/coronavirus-testing-emergency-room-doctor-cdc-departmenthealth-squawk-box.html
2
https://www.cdc.gov/malaria/resources/pdf/fsp/drugs/Chloroquine.pdf
3
Vincent, Martin J et al...
Please send us corrections, updates, or comments. Vaccines and
treatments are complementary. All practical, effective, and safe means should
be used based on risk/benefit analysis. No treatment, vaccine, or intervention
is 100% available and effective for all current and future variants. We do not
provide medical advice. Before taking any medication, consult a qualified
physician who can provide personalized advice and details of risks and
benefits based on your medical history and situation.
FLCCC and
WCH
provide treatment protocols.
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