A comprehensive review on the biological interest of quinoline and its derivatives
Matada et al.,
A comprehensive review on the biological interest of quinoline and its derivatives,
Bioorganic & Medicinal Chemistry, doi:10.1016/j.bmc.2020.115973 (Review)
Review of quinolone and derivatives, natural and drug sources, and biological activity.
Matada et al., 31 Dec 2020, peer-reviewed, 3 authors.
Abstract: Bioorg. Med. Chem. 32 (2021) 115973
Contents lists available at ScienceDirect
Bioorganic & Medicinal Chemistry
journal homepage: www.elsevier.com/locate/bmc
A comprehensive review on the biological interest of quinoline and
its derivatives
Basavarajaiah Suliphuldevara Matada a, *, Raviraj Pattanashettar b, Nagesh
Gunavanthrao Yernale c, *
a
b
c
PG Department of Chemistry, Vijaya College, Bengaluru 560 004, Karnataka, India
Salicylates and Chemicals Pvt. Ltd., Hyderabad 500 076, Telangana, India
Department of Chemistry, Guru Nanak First Grade Science, Commerce and Post Graduate College, Bidar 585 403, Karnataka, India
A R T I C L E I N F O
A B S T R A C T
Keywords:
Heterocyclic compounds
Quinolines
Natural sources
Marketed drugs
Approved drugs
Biological Interest
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a significant assembly
motif for the development of new drug entities. Quinoline and its derivatives tested with diverse biological
activity constitute an important class of compounds for new drug development. Therefore, many scientific
communities have developed these compounds as intent structure and evaluated their biological activities. The
present, review provides brief natural sources of quinoline and including a new extent of quinoline-based
marketed drugs. This review also confers information about the biological activities of quinoline derivatives
such as antibacterial, antifungal, antimycobacterial, antiviral, anti-protozoal, antimalarial, anticancer, cardio
vascular, CNS effects, antioxidant, anticonvulsant, analgesic, anti-inflammatory, anthelmintic and miscellaneous
activities.
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