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0 0.5 1 1.5 2+ Mortality 75% Improvement Relative Risk Mortality (b) 44% c19hcq.org Stricker et al. HCQ for COVID-19 META ANALYSIS Favors HCQ Favors control
Hydroxychloroquine Pre-Exposure Prophylaxis for COVID-19 in Healthcare Workers from India: A Meta-Analysis
Stricker et al., Journal of Infection and Public Health, doi:10.1016/j.jiph.2021.08.001 (meta analysis)
5 Aug 2021    Source   PDF   Share   Tweet
Meta analysis of 11 HCQ PrEP studies in India covering 7,616 healthcare workers, showing significantly lower cases with treatment.
Currently there are 86 HCQ pre-exposure prophylaxis studies and meta analysis shows:
OutcomeImprovement
Mortality31% lower [11‑46%]
Cases32% fewer [23‑40%]
risk of death, 75.0% lower, RR 0.25, p < 0.001, treatment 1,273, control 4,127, >=6 doses.
risk of death, 44.0% lower, RR 0.56, p = 0.004, treatment 3,489, control 4,127, any number of doses.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Stricker et al., 5 Aug 2021, peer-reviewed, 2 authors.
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