Abstract: medRxiv preprint doi: https://doi.org/10.1101/2021.11.05.21265569; this version posted November 5, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Evaluation of patients treated by telemedicine in the COVID-19 pandemic by a private clinic in São Paulo, Brazil: A non-randomized clinical trial preliminary study Michelle Chechter (MD)1*, Gustavo Maximiliano Dutra da Silva (MD, PhD)2, Thomas Gabriel Miklos (MD, PhD)3, Marta Maria Kemp (MD, PhD)4, Nilzio Antonio da Silva (MD, PhD)5, Gabriel Lober (MD)6, Marcela Ferreira Tavares Zanut (MD)7, Rute Alves Pereira e Costa8, Aline Pinheiro dos Santos Cortada9, Luciana de Nazare Lima da Cruz1, Paulo Macio Porto de Melo10, Bruno Campello de Souza11, Morton Aaron Scheinberg (MD, PhD)12** 1 CEO Centro Médico Mazzei, São Paulo, Brazil; 2 São Francisco University (USF), Bragança Paulista, Brazil; 3 Department of Obstetrics and Gynecology - Santa Casa of Sao Paulo Medical School, Sao Paulo (FCMSCSP), Brazil. 4 Kemp Institute of Integrative Health, São Paulo Brazil; 5 Federal University of Goias, Medical School, Department of Medical Clinic, Goiania, Brazil. 6 Laboratory DASA, São Paulo, Brazil; 7 Instituto CEMA, São Paulo, Brazil; 8 Sociedade Brasileira de Valorização das Sociedades Medicas—SOBEMED, São Paulo, Brazil; 9 Clinical Research Center of Associação de Assistência a Criança Deficiente, São Paulo, Brazil; 10 Departamento de Neurocirurgia, Hospital Militar de Area de São Paulo, Brazil 11 Departamento de Ciencias, Universidade Federal de Pernambuco, Recife, Brazil 12 Hospital Israelita Albert Einstein, São Paulo, Brazil. * Corresponding author: Michelle Chechter Av. Mazzei, 289 São Paulo – SP, Brasil. CEP: 02310-000 - Fone: +55 (11) 96316-2985 / (11) 2306-8120 E-mail: gumaxy@yahoo.com.br ** In memoriam NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. medRxiv preprint doi: https://doi.org/10.1101/2021.11.05.21265569; this version posted November 5, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Abstract Introduction: As a result of the coronavirus disease 2019 (COVID-19) pandemic the year 2020 brought major changes on the delivery of health care and face to face physician patient communication was significantly reduced and the practice of remote telehealth care using computer technology is assuming a standard of care, particularly, with COVID-19 patients with attempts to reduce viral spread. Objective: To describe the clinical practice experience using telemedicine towards COVID-19 and the respective clinical outcomes. Methods: We performed a pilot open-label non-randomized, controlled clinical trial. The patients were divided into four groups, according severity of symptoms: (1) asymptomatic, (2) mild symptoms, (3) moderate symptoms and (4) severe symptoms, and were followed up for five days, counted from the beginning of the symptoms. A drug intervention was performed in group 3, for which the protocol followed as suggested by the International Pulmonology Society’s consensus for adults with moderate..