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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Improvement in pneumon.. 57% Improvement Relative Risk c19hcq.org Chen et al. HCQ for COVID-19 RCT LATE TREATMENT Favors HCQ Favors control
Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial
Chen et al., medRxiv doi:10.1101/2020.03.22.20040758 (Preprint)
31 Mar 2020    Source   PDF   Share   Tweet
62 patients. RCT showing significantly faster recovery with HCQ. 13% progressed to severe cases in the control group, versus 0% for the treatment group. Significant improvement seen in pneumonia on chest CT for 61% of treated patients and 16% of control patients.
risk of no improvement in pneumonia at day 6, 57.0% lower, RR 0.43, p = 0.04, treatment 6 of 31 (19.4%), control 14 of 31 (45.2%), NNT 3.9.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Chen et al., 31 Mar 2020, Randomized Controlled Trial, China, preprint, 9 authors.
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Late treatment
is less effective
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