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0 0.5 1 1.5 2+ Case 60% Improvement Relative Risk Case (b) 35% Case (c) 23% c19hcq.org Badyal et al. HCQ for COVID-19 PrEP Is pre-exposure prophylaxis with HCQ beneficial for COVID-19? Prospective study of 2,090 patients in India Fewer cases with HCQ (p<0.000001) Badyal et al., J. the Association of Physicians of India, Volume 69, June 2021 Favors HCQ Favors control
Hydroxychloroquine for SARS CoV2 Prophylaxis in Healthcare Workers – A Multicentric Cohort Study Assessing Effectiveness and Safety
Badyal et al., Journal of the Association of Physicians of India, Volume 69, June 2021
Badyal et al., Hydroxychloroquine for SARS CoV2 Prophylaxis in Healthcare Workers – A Multicentric Cohort Study Assessing.., Journal of the Association of Physicians of India, Volume 69, June 2021
Jun 2021   Source   PDF  
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Prophylaxis study with 12,089 Indian healthcare workers, showing lower risk of COVID-19 cases with treatment, and increasingly lower risk for longer durations of HCQ prophylaxis. The appendices are not currently available.
risk of case, 60.1% lower, RR 0.40, p < 0.001, treatment 247 of 617 (40.0%), control 611 of 1,473 (41.5%), adjusted per study, odds ratio converted to relative risk, >=6 weeks, logistic regression.
risk of case, 35.1% lower, RR 0.65, p = 0.003, treatment 88 of 185 (47.6%), control 611 of 1,473 (41.5%), adjusted per study, odds ratio converted to relative risk, 4-5 weeks, logistic regression.
risk of case, 23.2% lower, RR 0.77, p = 0.04, treatment 80 of 181 (44.2%), control 611 of 1,473 (41.5%), adjusted per study, odds ratio converted to relative risk, 2-3 weeks, logistic regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Badyal et al., 7 Jun 2021, prospective, India, peer-reviewed, 18 authors.
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