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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality -20% Improvement Relative Risk c19hcq.org Mahévas et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data
Mahévas et al., BMJ 2020, 369, doi: https://doi.org/10.1136/bmj.m1844
14 May 2020    Source   PDF   Share   Tweet
Observational study of 181 patients with advanced disease requiring oxygen showing no benefit for HCQ. Power of study appears too low to support conclusions [bmj.com].
None of the 15 patients receiving HCQ+AZ were transferred to intensive care or died compared to 23% overall.
risk of death, 20.0% higher, HR 1.20, p = 0.75, treatment 9 of 84 (10.7%), control 8 of 89 (9.0%), adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mahévas et al., 14 May 2020, retrospective, France, peer-reviewed, 34 authors, average treatment delay 7.0 days.
All Studies   Meta Analysis   Submit Updates or Corrections
This PaperHCQAll
Late treatment
is less effective
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