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0 0.5 1 1.5 2+ Mortality 74% Improvement Relative Risk c19hcq.org Lauriola et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Effect of combination therapy of hydroxychloroquine and azithromycin on mortality in COVID‐19 patients
Lauriola et al., Clinical and Translational Science, doi:10.1111/cts.12860
14 Sep 2020    Source   PDF   Share   Tweet
Retrospective 377 patients, 73% reduction in mortality with HCQ+AZ, adjusted hazard ratio HR 0.27 [0.17-0.41]. Mean age 71.8. No serious adverse events. Subject to incomplete adjustment for confounders.
risk of death, 73.5% lower, HR 0.27, p < 0.001, treatment 102 of 297 (34.3%), control 35 of 63 (55.6%), NNT 4.7, adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lauriola et al., 14 Sep 2020, retrospective, Italy, peer-reviewed, mean age 71.8, 10 authors.
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Late treatment
is less effective
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