Characteristics and Obstetric Outcomes in Women With Autoimmune Rheumatic Disease During the COVID-19 Pandemic in Qatar
Satti et al.,
Characteristics and Obstetric Outcomes in Women With Autoimmune Rheumatic Disease During the COVID-19 Pandemic..,
Cureus, doi:10.7759/cureus.24382
Retrospective 80 consecutive pregnant patients with autoimmune rheumatic diseases in Qatar, showing lower risk of COVID-19 cases with HCQ prophylaxis.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details.
risk of case, 61.5% lower, RR 0.39, p = 0.04, treatment 10 of 63 (15.9%), control 7 of 17 (41.2%), NNT 4.0.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Satti et al., 22 Apr 2022, retrospective, Qatar, peer-reviewed, 6 authors.
Contact:
salemadi@hamad.qa.
Abstract: Open Access Original
Article
DOI: 10.7759/cureus.24382
Characteristics and Obstetric Outcomes in
Women With Autoimmune Rheumatic Disease
During the COVID-19 Pandemic in Qatar
Review began 04/11/2022
Review ended 04/21/2022
Eman Satti 1 , Monika Ostensen 2 , soha darrgham 3 , Nawal Hadwan 4 , Hadeel Ashour 4 , Samar AL Emadi 4
Published 04/22/2022
© Copyright 2022
Satti et al. This is an open access article
distributed under the terms of the Creative
Commons Attribution License CC-BY 4.0.,
1. Intenal Medicine, Rheumatology Section, Hamad Medical Corporation, Doha, QAT 2. Department of Rheumatology,
Sorlandet Hospital, Kristiansand, NOR 3. Biostatistics, Epidemiology, and Biomathematics Research Core, Weill
Cornell Medicine, Doha, QAT 4. Internal Medicine, Rheumatology Section, Hamad Medical Corporation, Doha, QAT
which permits unrestricted use, distribution,
and reproduction in any medium, provided
the original author and source are credited.
Corresponding author: Samar AL Emadi, salemadi@hamad.qa
Abstract
Objective: Pregnant women with autoimmune rheumatic diseases are considered to have a high risk of
obstetric complications with the emergence of the Coronavirus disease (COVID-19) pandemic. Therefore,
we aimed to assess the impact of COVID-19 on this high-risk group.
Methods: This cross-sectional cohort study (March to December 2020) was conducted at the largest tertiary
center in Qatar (Hamad Medical Corporation). Eighty consecutive patients following up at the center during
pregnancy were surveyed through telephonic interviews. Data on COVID-19 and pregnancy outcomes were
extracted from electronic hospital records.
Results: Eighty pregnant women with autoimmune rheumatic diseases were included. Among them, 17
(21.3%) (95% confidence interval [CI]: 12.9-31.8%) were diagnosed with COVID-19, five were hospitalized,
and only one required intensive care unit admission. The proportion of adverse obstetric outcomes in the
cohort was 29.5% (n = 23; 95% CI: 19.7-40.9%). Prematurity (n = 14; 19.4%) and caesarean section (n = 30;
41.1%) were the most prevalent adverse events. There was no statistical difference in adverse pregnancy
outcomes between women with and without COVID-19.
Conclusion: COVID-19 did not affect pregnancy outcomes in women with autoimmune rheumatic diseases.
Categories: Obstetrics/Gynecology, Infectious Disease, Rheumatology
Keywords: autoimmune rheumatic diseases, caesarean, covid-19, prematurity, pregnancy
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