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0 0.5 1 1.5 2+ Mortality 16% Improvement Relative Risk c19hcq.org Roig et al. HCQ for COVID-19 LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 79 patients in Spain No significant difference in mortality Roig et al., Revista Espanola de Quimioterapia, doi:10.37201/req/130.2020 Favors HCQ Favors control
Clinical and pharmacological data in COVID-19 hospitalized nonagenarian patients
Roig et al., Revista Espanola de Quimioterapia, doi:10.37201/req/130.2020
Roig et al., Clinical and pharmacological data in COVID-19 hospitalized nonagenarian patients, Revista Espanola de Quimioterapia, doi:10.37201/req/130.2020
Jan 2021   Source   PDF  
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Retrospective 79 hospitalized nonagenarian patients showing unadjusted HCQ mortality RR 0.84, p = 0.76.
Although the 16% lower mortality is not statistically significant, it is consistent with the significant 22% lower mortality [18‑27%] from meta analysis of the 232 mortality results to date. This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of death, 15.6% lower, RR 0.84, p = 0.76, treatment 33 of 67 (49.3%), control 7 of 12 (58.3%), NNT 11.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Roig et al., 31 Jan 2021, retrospective, Spain, peer-reviewed, 6 authors.
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Late treatment
is less effective
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