Abstract: Heart & Lung 50 (2021) 28 32 Contents lists available at ScienceDirect Heart & Lung journal homepage: www.heartandlung.com Outcomes of patients with COVID-19 in the intensive care unit in Mexico: A multicenter observational study
e Silvio A. Namendys-Silva, MD, MSc, FCCP, FCCMa,h,*, Pedro E. Alvarado-Avila, MDa, a,b a Guillermo Domínguez-Cherit, MD, FCCM , Eduardo Rivero-Sigarroa, MD ,
nchez-Hurtado, MDc, Alan Gutie
rrez-Villasen ~ or, MDd, Luis A. Sa
lez, MDd, Heber Rodríguez-Bautista, MDa, Alondra García-Briones, MDd, Juan P. Romero-Gonza
stor G. Cruz-Ruiz, MDf, María O. Gonza
lez-Herrera, MDg,
sar E. Garnica-Camacho, MDe, Ne Ce h h
rrez, MD ,
n, MD , Manuel A. Guerrero-Gutie Francisco J. García-Guille i

L. Canto-Castro, MDj,


Jose D. Salmeron-Gonzalez, MD , Laura Romero-Gutierrez, MDc, Jose Victor H. Cervantes, MDk, on behalf of the Mexico COVID-19 Critical Care Collaborative Group
n, Mexico City 14000, Mexico
n Salvador Zubira Instituto Nacional de Ciencias Me
dicas y Nutricio
gico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Mexico City, Mexico Tecnolo c Hospital de Especialidades del Centro Me
dico Nacional Siglo XXI, IMSS, Mexico City, Mexico d Hospital Me
dica Sur, Mexico City, Mexico e Hospital General de Zona No.1 “Dr. Enrique Von Borstel Labastida”, IMSS, La Paz, Baja California Sur, Mexico f Hospital General de Zona No. 1, “Dr. Demetrio Mayoral Pardo”, IMSS, Oaxaca, Mexico g Hospital General de Zona 1, IMSS, Tlaxcala, Mexico h Instituto Nacional de Cancerología (INCan), Mexico City, Mexico i
n, Mexico Hospital General “Dr. Miguel Silva”, Morelia, Michoaca j
n, Mexico Unidad Me
dica de Alta Especialidad "Ignacio García Te
llez", IMSS, Me
rida, Yucata k
n, Guanajuato, Mexico Hospital General Regional No. 58, IMSS, Leo a b A R T I C L E I N F O Article History: Received 23 July 2020 Revised 16 October 2020 Accepted 20 October 2020 Available online 21 October 2020 Keywords: COVID-19 SARS-CoV-2 infection Coronavirus Intensive care unit Mexico Outcomes A B S T R A C T Background: As of June 15, 2020, a cumulative total of 7,823,289 confirmed cases of COVID-19 have been reported across 216 countries and territories worldwide. However, there is little information on the clinical characteristics and outcomes of critically ill patients with severe COVID-19 who were admitted to intensive care units (ICUs) in Latin America. The present study evaluated the clinical characteristics and outcomes of critically ill patients with severe COVID-19 who were admitted to ICUs in Mexico. Methods: This was a multicenter observational study that included 164 critically ill patients with laboratoryconfirmed COVID-19 who were admitted to 10 ICUs in Mexico, from April 1 to April 30, 2020. Demographic data, comorbid conditions, clinical presentation, treatment, and outcomes were collected and analyzed. The date of final follow-up was June 4, 2020. Results: A total of 164 patients with severe COVID-19 were included in this study. The mean age of patients was 57.3 years (SD 13.7), 114 (69.5%) were men, and 6.0% were healthcare workers. Comorbid conditions were common in patients with critical COVID-19: 38.4% of patients had hypertension and 32.3% had diabetes. Compared to survivors, nonsurvivors were older and more likely to have diabetes, hypertension or other conditions. Patients presented to the hospital a median of 7 days (IQR 4.5 9) after symptom onset. The most common presenting symptoms were shortness of..