COVID-19 Case Series at UnityPoint Health St. Luke’s Hospital in Cedar Rapids, IA

DOI record: { "DOI": "10.1101/2020.07.17.20156521", "URL": "http://dx.doi.org/10.1101/2020.07.17.20156521", "abstract": "<jats:title>Abstract</jats:title><jats:p>A retrospective, descriptive study of all patients tested for SARS-CoV2 on admission for illness to a community hospital in Iowa from 3/21/20 thru 6/14/20 consisted of evaluation as to demographics, presentation and hospital course. Ninety-one patients were SARS-CoV2 PCR+ with 63% being male and a median age of 60. Cardiovascular disease was a significant comorbidity in the PCR+ group. Fever, cough, dyspnea, nausea, emesis, diarrhea, headache and myalgias were significantly more common in that group, as was an elevated CRP, LDH, serum ferritin and transaminases. Overall survival of the COVID-19 patients was 88%, 77% in the critically ill, 59% of those mechanically ventilated and 33% of those requiring new dialysis. Survival was 93% in those not receiving any antivirals. Survival of those treated with hydroxychloroquine-azithromycin was 92%, compared to 86% of those treated with hydroxychloroquine alone. The latter two groups were significantly more ill than the untreated group. A transition from an early intubation strategy to aggressive utilization of high flow nasal cannula and noninvasive ventilation(i.e BiPAP) was successful in freeing up ICU resources.</jats:p>", "accepted": { "date-parts": [ [ 2020, 7, 19 ] ] }, "author": [ { "affiliation": [], "family": "Edwards", "given": "Dianna", "sequence": "first" }, { "affiliation": [], "family": "McGrail", "given": "Daniel", "sequence": "additional" } ], "container-title": [], "content-domain": { "crossmark-restriction": false, "domain": [] }, "created": { "date-parts": [ [ 2020, 7, 19 ] ], "date-time": "2020-07-19T15:55:12Z", "timestamp": 1595174112000 }, "deposited": { "date-parts": [ [ 2021, 1, 15 ] ], "date-time": "2021-01-15T07:25:38Z", "timestamp": 1610695538000 }, "group-title": "Infectious Diseases (except HIV/AIDS)", "indexed": { "date-parts": [ [ 2023, 8, 28 ] ], "date-time": "2023-08-28T13:01:47Z", "timestamp": 1693227707678 }, "institution": [ { "name": "medRxiv" } ], "is-referenced-by-count": 2, "issued": { "date-parts": [ [ 2020, 7, 19 ] ] }, "link": [ { "URL": "https://syndication.highwire.org/content/doi/10.1101/2020.07.17.20156521", "content-type": "unspecified", "content-version": "vor", "intended-application": "similarity-checking" } ], "member": "246", "original-title": [], "posted": { "date-parts": [ [ 2020, 7, 19 ] ] }, "prefix": "10.1101", "published": { "date-parts": [ [ 2020, 7, 19 ] ] }, "publisher": "Cold Spring Harbor Laboratory", "reference": [ { "DOI": "10.1001/jama.2020.4326", "doi-asserted-by": "publisher", "key": "2021011423251240000_2020.07.17.20156521v1.1" }, { "DOI": "10.1056/NEJMoa2004500", "doi-asserted-by": "publisher", "key": "2021011423251240000_2020.07.17.20156521v1.2" }, { "DOI": "10.1016/j.ijantimicag.2020.106020", "doi-asserted-by": "crossref", "key": "2021011423251240000_2020.07.17.20156521v1.3", "unstructured": "Fantini J , et al. 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