Abstract: medRxiv preprint doi: https://doi.org/10.1101/2020.12.11.20247437; this version posted December 14, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Clinical and Demographic Characteristics of COVID-19 Patients Admitted in a Tertiary Care Hospital in the Dominican Republic Authors: David De Luna1, Yori Roque1, Nicolás Batlle1, Katherine Gómez1, Miguelina Jáquez1, Brinia Cabrera1, Lissa de la Cruz1, Osvaldo,Tavárez1, Rossy Belliard1, José Javier Sanchez2 Affiliations: 1 HOMS - COVID Study Team, Hospital Metropolitano de Santiago, Santiago de los Caballeros, Dominican Republic 2 Pontificia Universidad Católica Madre y Maestra, Santiago de los Caballeros, Dominican Republic Abstract To present clinical and demographic characteristics of COVID-19 patients admitted to Hospital Metropolitano de Santiago in Dominican Republic, we analyzed electronic medical records of all hospitalized patients clinically admitted as viral pneumonia through March - April, 2020. Of 374 patients, 150 (40.1%) laboratory confirmed, were included in this study. Most of the patients were men (104 / 69.3%) with a median (IQR 44 - 66) age of 54. Hypertension (83 / 55.3%) and diabetes mellitus (49 / 32.7%) were the most common comorbidities, whereas fever (120 / 80%), cough (79 / 52.7%) and fatigue (60 / 40%) were the most common presenting symptoms. 28 (18.7%) patients required admission to the intensive care unit, of them, 26 patients (17.3%) required mechanical ventilation. The overall mortality rate was 10.7% Higher levels of inflammatory markers were associated with longer length of stay (LOS). This findings indulge information that could contribute to stratify patients at higher risk of complications. Background By the end of 2019, the world began to confront numerous cases of viral pneumonia, initially detected in Wuhan, China, which quickly spread all around the globe, becoming a pandemic.1 Since its naming and further description, much is known about SARS-CoV-2 and its associated disease, COVID - 19, allowing health personnel a better understanding of its dynamics and outcomes. To date, almost a year after these first cases, more than 70 million people have been affected, and more thank 1,5 million have died.2 Recently, several drugs have demonstrated beneficial effects in COVID-19, including antivirals that can reduce viral replication and lessens the length of stay, but none have been able to prevent new infections or act as post exposure prophylactic agent. NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. medRxiv preprint doi: https://doi.org/10.1101/2020.12.11.20247437; this version posted December 14, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . The Dominican Republic (DR) has been struggling with COVID-19 since the first confirmed case back in March 2020, in an italian tourist in the northern part of the country. By then, the country was in the middle of an electoral process, which is believed contributed to the rapid propagation and community transmission of..