Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
Top
Results
Abstract
All HCQ studies
Meta analysis
 
Feedback
Home
next
study
previous
study
c19hcq.org COVID-19 treatment researchHCQHCQ (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   

Covid-19 in transplant recipients: the spanish experience

Coll et al., American Journal of Transplantation, doi:10.1111/ajt.16369
Oct 2020  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Mortality 46% Improvement Relative Risk HCQ for COVID-19  Coll et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 635 patients in Spain Lower mortality with HCQ (p=0.000018) c19hcq.org Coll et al., American J. Transplantation, Oct 2020 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now with p < 0.00000000001 from 417 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 102 treatments. c19hcq.org
Retrospective 652 transplant recipient patients in Spain showing 46% lower mortality for patients treated with HCQ, unadjusted relative risk RR 0.54, p<0.0001.
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of death, 45.6% lower, RR 0.54, p < 0.001, treatment 55 of 307 (17.9%), control 108 of 328 (32.9%), NNT 6.7.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Coll et al., 23 Oct 2020, retrospective, Spain, peer-reviewed, median age 61.0, 29 authors.
This PaperHCQAll
COVID-19 in transplant recipients: The Spanish experience
Elisabeth Coll, Mario Fernández-Ruiz, J Emilio Sánchez-Álvarez, José R Martínez-Fernández, Orcid ID Marta Crespo, Jorge Gayoso, Teresa Bada-Bosch, Federico Oppenheimer, Francesc Moreso, María O López-Oliva, Edoardo Melilli, Marisa L Rodríguez-Ferrero, Carlos Bravo, Elena Burgos, Carme Facundo, Inmaculada Lorenzo, Íñigo Yañez, Cristina Galeano, Ana Roca, Mercedes Cabello, Manuel Gómez-Bueno, Madolores García-Cosío, Javier Graus, Laura Lladó, Alicia De Pablo, Carmelo Loinaz, Beatriz Aguado, Domingo Hernández, Orcid ID Beatriz Domínguez-Gil
American Journal of Transplantation, doi:10.1111/ajt.16369
Group for the Study of Infection in Transplantation and the Immunocompromised Host (GESITRA-IC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).
DISCLOSURE The authors of this manuscript have no conflicts of interest to disclose as described by the American Journal of Transplantation. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. Accepted Article TABLES Table 1 . Baseline characteristics of solid organ and hematopoietic stem cell transplant recipients with COVID-19 and therapies used, overall and according to the transplant type a . BASELINE Accepted Article This article is protected by copyright. All rights reserved Accepted Article This article is protected by copyright. All rights reserved a Protease inhibitors in any combination. b Defined as the administration of bolus of corticosteroids, initiation of corticosteroids, or increase of baseline doses. ARDS: acute respiratory distress syndrome; AZT: azithromycin; HCQ: hydroxychloroquine. Accepted Article This article is protected by copyright. All rights reserved
References
Aguilar, Arias, Bravo, Puerta De Hierro, None
Aigner, Dittmer, Kamler, COVID-19 in a lung transplant recipient, J Heart Lung Transplant, doi:10.1016/j.healun.2020.04.004
Akalin, Azzi, Bartash, Covid-19 and kidney transplantation, N Engl J Med, doi:10.1056/NEJMc2011117
Albacete, None
Alberici, Delbarba, Manenti, Management of patients on dialysis and with kidney transplant during SARS-COV-2 (COVID-19) pandemic in Brescia, Italy, Kidney Int Rep, doi:10.1016/j.ekir.2020.04.001
Alcolea, Espinosa, María, González-García, Paz, None
Alghamdi, Mushtaq, Awn, Shalhoub, MERS CoV infection in two renal transplant recipients: case report, Am J Transplant, doi:10.1111/ajt.13085
Alonso, Andrés, Hernández-Vicente, Paciello, Quezada et al., None
Amir Shabaka, Fundación Alcorcón, None
Aragoncillo, Beléndez, Blázquez, Kwon, Ortiz et al., None
Ariceta, Sellares, Castells, Pont, Vall D'hebrón, None
Auxiliadora Mazuecos, Puerta, None
Baliellas, Cachero, González-Costello, Manito, Bellvitge, None
Banerjee, Popoola, Shah, COVID-19 infection in kidney transplant recipients, Kidney Int, doi:10.1016/j.kint.2020.03.018
Begoña Navas, Hla Moncloa, None
Beigel, Tomashek, Dodd, Remdesivir for the treatment of Covid-19 -Preliminary report, N Engl J Med
Beneyto, José, Piñana, Ramos, Sales et al., None
Bhoori, Rossi, Citterio, COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy, Lancet Gastroenterol Hepatol, doi:10.1016/S2468-1253(20)30116-3
Billah, Santeusanio, Delaney, A catabolic state in a kidney transplant recipient with COVID-19, Transpl Int, doi:10.1111/tri.13635
Blanco, Hernández-Gallego, Infanta, None
Blasco, Castel, Coca, Rovira, Clinic, None
Brossa, Mirabet, Pau, None
Buxeda, María, Redondo, None
Cabello, Son, Espases, None
Cabezas, Muñoz-Cepeda, Toledo, None
Calvo, None
Canal, Puigvert, None
Cao, Wang, Wen, A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19, N Engl J Med, doi:10.1056/NEJMoa2001282
Castro, CATA, Andalucía
Cavalcanti, Zampieri, Rosa, Hydroxychloroquine with or without azithromycin in mildto-moderate Covid-19, N Engl J Med
Cobo, Fábrega, Víctor, Mora, Ruiz San Millán et al., None
Colmenero, Rodríguez-Perálvarez, Salcedo, Epidemiological pattern, incidence and outcomes of COVID-19 in liver transplant patients, J Hepatol
Cornago, Fundación, Díaz, None
Cravedi, Suraj, Azzi, COVID-19 and kidney transplantation: Results from the TANGO International Transplant Consortium, Am J Transplant, doi:10.1111/ajt.16185
Crespo-Leiro, Otero, Santiago, de Compostela
Cruzado, De Elche, None
Cuiña, Peláez, Pontevedra, None
De Juan, De, None
Domínguez-Gil, Coll, Fernández-Ruiz, COVID-19 in Spain: transplantation in the midst of the pandemic, Am J Transplant, doi:10.1111/ajt.15983
Díaz, Sofía, None
Díaz-Mareque, María, Coruña, None
Fernández-Girón, Saldaña, Jerez De La Frontera, None
Fernández-Ruiz, Andrés, Loinaz, COVID-19 in solid organ transplant recipients: a singlecenter case series from Spain, Am J Transplant, doi:10.1111/ajt.15929
Fernández-Tagarro, González-Rodríguez, María, Pérez-Tamajón, Ramírez-Puga et al., None
Fontana, Alfano, Mori, Covid-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine, Am J Transplant, doi:10.1111/ajt.15935
Fraile, Heras, Prieto, Tabernero, Salamanca, None
Franco, López-Vilella, Santiago, De Alicante, None
Gallardo, González-Grande, López-Jiménez, Nieto, Regional de Málaga
Garbino, Crespo, Aubert, A prospective hospital-based study of the clinical impact of nonsevere acute respiratory syndrome (Non-SARS)-related human coronavirus infection, Clin Infect Dis
Garra, None
Gascón, Polanco, None
Geleris, Sun, Platt, Observational study of hydroxychloroquine in hospitalized patients with Covid-19, N Engl J Med, doi:10.1056/NEJMoa2012410
Giorgi, De, Princesa, None
González-Vicent, Jesús, None
Grande, Zamora, None
Guan, Ni, Hu, Clinical characteristics of Coronavirus Disease 2019 in China, N Engl J Med, doi:10.1056/NEJMoa2002032
Gómez-Giralda, Méndez-Pascual, Hortega, None
Hammami, Garibaldi, Shah, Clinical Course of COVID-19 in a liver transplant recipient on hemodialysis and response to tocilizumab therapy: a case report, Am J Transplant, doi:10.1111/ajt.15985
Heras, Meseguer, None
Hernando, Galdakao Usansolo, None
Herrera, Ramón, None
Horby, Lim, Dexamethasone in hospitalized Patients with Covid-19 -Preliminary report, N Engl J Med
Huang, Wang, Li, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, doi:10.1016/S0140-6736(20)30183-5
Ison, Hager, Blumberg, Donor-derived disease transmission events in the United States: data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee, Am J Transplant, doi:10.1111/j.1600-6143.2009.02700.x
José, Herrero, Martín-Moreno, Rábago, Navarra, None
José, Pérez, Gastaca, Mateos, De Cruces, Sofía Zárraga
José, Álamo, Bernal, Martín-González, José et al., del Rocío
Juan, Martínez-Ocaña, Taulí, None
Juega, Andrés Accepted Article This article is protected by copyright
Jurado, María, Nogueras, María, Ruiz Fuentes et al., None
Kanter, Peset, None
Kates, Fisher, Stankiewicz-Karita, Earliest cases of coronavirus disease 2019 (COVID-19) identified in solid organ transplant recipients in the United States, Am J Transplant, doi:10.1111/ajt.15944
Kim, Kwon, Paek, Two distinct cases with COVID-19 in kidney transplant recipients, Am J Transplant, doi:10.1111/ajt.15947
Kuderer, Choueiri, Shah, Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study, Lancet, doi:10.1016/S0140-6736(20)31187-9
Kumar, Tellier, Draker, Severe acute respiratory syndrome (SARS) in a liver transplant recipient and guidelines for donor SARS screening, Am J Transplant, doi:10.1034/j.1600-6143.2003.00197.x
Liang, Liang, Ou, Development and validation of a clinical risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19, JAMA Intern Med, doi:10.1001/jamainternmed.2020.2033
Lozano, Basurto, None
Lucas Lage, Cunqueiro, None
López, Vázquez, Alonso-Titos, Recommendations on management of the SARS-CoV-2 coronavirus pandemic (Covid-19) in kidney transplant patients, Nefrologia, doi:10.1016/j.nefro.2020.03.002
Manrique, Zudaire, Navarra, None
Martín-Calvo, Montero, Rodríguez-Benot, Sofía, None
María, Aladrén, María, Blasco, Gutiérrez-Dalmau et al., None
María, Del Barrio, De Jaén, None
María, Fernández-Reyes, Segovia, None
María, González-Diéguez, Lambert, Pérez-Fernández, María et al., Central de Asturias
María, Moral, None
María, Rodrigo, Vallejo, Donosti, None
María, Rodríguez-Pérez, Virgen De La Macarena, None
Meziyerh, Zwart, Van Etten, Severe COVID-19 in a renal transplant recipient: a focus on pharmacokinetics, Am J Transplant, doi:10.1111/ajt.15943
Michaels, Hoz, Isakov, Coronavirus Disease 2019: implications of emerging infections for transplantation, Am J Transplant, doi:10.1111/ajt.15832
Mitjà, Corbacho-Monne, Ubals, Hydroxychloroquine for early treatment of adults with mild Covid-19: A randomized-controlled trial, Clin Infect Dis, doi:10.1093/cid/ciaa1009
Montenegro, Duran I Reynals, None
Montoro, Requena, None
Nair, Jandovitz, Hirsch, COVID-19 in kidney transplant recipients, Am J Transplant, doi:10.1111/ajt.15967
Ochoa, None
Paraíso, Del Henares, None
Pastor, Augusti, None
Pedro, None
Pereira, Mohan, Cohen, COVID-19 in solid organ transplant recipients: initial report from the US Epicenter, Am J Transplant, doi:10.1111/ajt.15941
Ramírez-Romero, Saura, Virgen, de la Arrixaca
Ranieri, Rubenfeld, Thompson, Acute respiratory distress syndrome: the Berlin Definition, JAMA, doi:10.1001/jama.2012.5669
Real, None
Ritschl, Nevermann, Wiering, Solid organ transplantation programs facing lack of empiric evidence in the COVID-19 pandemic: a by-proxy society recommendation consensus approach, Am J Transplant, doi:10.1111/ajt.15933
Sanchinarro, None
Sanders, Monogue, Jodlowski, Pharmacologic treatments for Coronavirus Disease 2019 (COVID-19): A review, JAMA, doi:10.1001/jama.2020.6019
Santana, Doctor Negrín, None
Secundino Cigarran, Da Mariña, None
Siddiqi, Mehra, COVID-19 illness in native and immunosuppressed states: A clinical-therapeutic staging proposal, J Heart Lung Transplant, doi:10.1016/j.healun.2020.03.012
Simal, Bierzo, None
Skipper, Pastick, Engen, Hydroxychloroquine in nonhospitalized adults with early COVID-19: A randomized trial, Ann Intern Med, doi:10.7326/M20-4207
Sánchez-Álvarez, Pérez-Fontán, Jiménez-Martín, SARS-CoV-2 infection in patients on renal replacement therapy. Report of the COVID-19 Registry of the Spanish Society of Nephrology (SEN), Nefrología, doi:10.1016/j.nefro.2020.04.002
Veronese, Demurtas, Yang, Use of corticosteroids in Coronavirus Disease 2019 pneumonia: A systematic review of the literature, Front Med, doi:10.3389/fmed.2020.00170
Vázquez, Ocatt, None, REFERENCES
Who Director, s opening remarks at the media briefing on COVID-19 -20
Wu, Chen, Cai, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China, JAMA Intern Med, doi:10.1001/jamainternmed.2020.0994
Wu, Mcgoogan, Characteristics of and important lessons from the Coronavirus Disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention, JAMA, doi:10.1001/jama.2020.2648
Xu, Han, Li, Immunosuppression drug-related and clinical manifestation of Coronavirus disease 2019: A therapeutical hypothesis, Proc Natl Acad Sci U S A, doi:10.1073/pnas.2005615117
Zhou, Yu, Du, Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study, Lancet, doi:10.1016/S0140-6736(20)30566-3
Zhu N Zhang, A novel coronavirus from patients with pneumonia in China, 2019, N Engl J Med, doi:10.1056/NEJMoa2001017
Zhu, Gong, Liu, Coronavirus Disease 2019 pneumonia in immunosuppressed renal transplant recipients: a summary of 10 confirmed cases in Wuhan, China, Eur Urol, doi:10.1016/j.eururo.2020.03.039
Álamo, María, Morales, Guadalajara, None
{ 'indexed': {'date-parts': [[2024, 4, 4]], 'date-time': '2024-04-04T11:56:52Z', 'timestamp': 1712231812253}, 'reference-count': 53, 'publisher': 'Elsevier BV', 'issue': '5', 'license': [ { 'start': { 'date-parts': [[2021, 5, 1]], 'date-time': '2021-05-01T00:00:00Z', 'timestamp': 1619827200000}, 'content-version': 'tdm', 'delay-in-days': 0, 'URL': 'https://www.elsevier.com/tdm/userlicense/1.0/'}, { 'start': { 'date-parts': [[2022, 11, 10]], 'date-time': '2022-11-10T00:00:00Z', 'timestamp': 1668038400000}, 'content-version': 'vor', 'delay-in-days': 558, 'URL': 'http://creativecommons.org/licenses/by-nc-nd/4.0/'}], 'content-domain': { 'domain': ['amjtransplant.org', 'elsevier.com', 'sciencedirect.com'], 'crossmark-restriction': True}, 'published-print': {'date-parts': [[2021, 5]]}, 'DOI': '10.1111/ajt.16369', 'type': 'journal-article', 'created': { 'date-parts': [[2020, 10, 24]], 'date-time': '2020-10-24T03:14:22Z', 'timestamp': 1603509262000}, 'page': '1825-1837', 'update-policy': 'http://dx.doi.org/10.1016/elsevier_cm_policy', 'source': 'Crossref', 'is-referenced-by-count': 137, 'title': 'COVID-19 in transplant recipients: The Spanish experience', 'prefix': '10.1016', 'volume': '21', 'author': [ {'given': 'Elisabeth', 'family': 'Coll', 'sequence': 'first', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-0315-8001', 'authenticated-orcid': False, 'given': 'Mario', 'family': 'Fernández-Ruiz', 'sequence': 'additional', 'affiliation': []}, { 'given': 'J. Emilio', 'family': 'Sánchez-Álvarez', 'sequence': 'additional', 'affiliation': []}, { 'given': 'José R.', 'family': 'Martínez-Fernández', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-6992-6379', 'authenticated-orcid': False, 'given': 'Marta', 'family': 'Crespo', 'sequence': 'additional', 'affiliation': []}, {'given': 'Jorge', 'family': 'Gayoso', 'sequence': 'additional', 'affiliation': []}, {'given': 'Teresa', 'family': 'Bada-Bosch', 'sequence': 'additional', 'affiliation': []}, {'given': 'Federico', 'family': 'Oppenheimer', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-7267-3963', 'authenticated-orcid': False, 'given': 'Francesc', 'family': 'Moreso', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-3503-3518', 'authenticated-orcid': False, 'given': 'María O.', 'family': 'López-Oliva', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-6965-3745', 'authenticated-orcid': False, 'given': 'Edoardo', 'family': 'Melilli', 'sequence': 'additional', 'affiliation': []}, { 'given': 'Marisa L.', 'family': 'Rodríguez-Ferrero', 'sequence': 'additional', 'affiliation': []}, {'given': 'Carlos', 'family': 'Bravo', 'sequence': 'additional', 'affiliation': []}, {'given': 'Elena', 'family': 'Burgos', 'sequence': 'additional', 'affiliation': []}, {'given': 'Carme', 'family': 'Facundo', 'sequence': 'additional', 'affiliation': []}, {'given': 'Inmaculada', 'family': 'Lorenzo', 'sequence': 'additional', 'affiliation': []}, {'given': 'Íñigo', 'family': 'Yañez', 'sequence': 'additional', 'affiliation': []}, {'given': 'Cristina', 'family': 'Galeano', 'sequence': 'additional', 'affiliation': []}, {'given': 'Ana', 'family': 'Roca', 'sequence': 'additional', 'affiliation': []}, {'given': 'Mercedes', 'family': 'Cabello', 'sequence': 'additional', 'affiliation': []}, {'given': 'Manuel', 'family': 'Gómez-Bueno', 'sequence': 'additional', 'affiliation': []}, {'given': 'MaDolores', 'family': 'García-Cosío', 'sequence': 'additional', 'affiliation': []}, {'given': 'Javier', 'family': 'Graus', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-3717-3306', 'authenticated-orcid': False, 'given': 'Laura', 'family': 'Lladó', 'sequence': 'additional', 'affiliation': []}, {'given': 'Alicia', 'family': 'de Pablo', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-1873-0568', 'authenticated-orcid': False, 'given': 'Carmelo', 'family': 'Loinaz', 'sequence': 'additional', 'affiliation': []}, {'given': 'Beatriz', 'family': 'Aguado', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-5469-2119', 'authenticated-orcid': False, 'given': 'Domingo', 'family': 'Hernández', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-5695-8993', 'authenticated-orcid': False, 'given': 'Beatriz', 'family': 'Domínguez-Gil', 'sequence': 'additional', 'affiliation': []}], 'member': '78', 'reference': [ { 'issue': '10223', 'key': '10.1111/ajt.16369_bib1', 'doi-asserted-by': 'crossref', 'first-page': '497', 'DOI': '10.1016/S0140-6736(20)30183-5', 'article-title': 'Clinical features of patients infected with 2019 novel coronavirus in ' 'Wuhan, China', 'volume': '395', 'author': 'Huang', 'year': '2020', 'journal-title': 'Lancet.'}, { 'issue': '8', 'key': '10.1111/ajt.16369_bib2', 'doi-asserted-by': 'crossref', 'first-page': '727', 'DOI': '10.1056/NEJMoa2001017', 'article-title': 'A novel coronavirus from patients with pneumonia in China, 2019', 'volume': '382', 'author': 'Zhu', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib3', 'unstructured': 'John Hopkins University of Medicine. Coronavirus Resource Center. ' 'https://coronavirus.jhu.edu/map.html. Accessed May 2020'}, { 'key': '10.1111/ajt.16369_bib4', 'unstructured': 'WHO Director-General’s opening remarks at the media briefing on COVID-19 ' '- 20 March 2020. ' 'https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---20-march-2020. ' 'Accessed August 2020'}, { 'issue': '13', 'key': '10.1111/ajt.16369_bib5', 'doi-asserted-by': 'crossref', 'first-page': '1239', 'DOI': '10.1001/jama.2020.2648', 'article-title': 'Characteristics of and important lessons from the Coronavirus Disease ' '2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases ' 'from the Chinese Center for Disease Control and Prevention', 'volume': '323', 'author': 'Wu', 'year': '2020', 'journal-title': 'JAMA.'}, { 'issue': '10229', 'key': '10.1111/ajt.16369_bib6', 'doi-asserted-by': 'crossref', 'first-page': '1054', 'DOI': '10.1016/S0140-6736(20)30566-3', 'article-title': 'Clinical course and risk factors for mortality of adult inpatients with ' 'COVID-19 in Wuhan, China: a retrospective cohort study', 'volume': '395', 'author': 'Zhou', 'year': '2020', 'journal-title': 'Lancet.'}, { 'issue': '8', 'key': '10.1111/ajt.16369_bib7', 'doi-asserted-by': 'crossref', 'first-page': '2254', 'DOI': '10.1111/ajt.15985', 'article-title': 'Clinical Course of COVID-19 in a liver transplant recipient on ' 'hemodialysis and response to tocilizumab therapy: a case report', 'volume': '20', 'author': 'Hammami', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '9', 'key': '10.1111/ajt.16369_bib8', 'doi-asserted-by': 'crossref', 'first-page': '1140', 'DOI': '10.1111/tri.13635', 'article-title': 'A catabolic state in a kidney transplant recipient with COVID-19', 'volume': '33', 'author': 'Billah', 'year': '2020', 'journal-title': 'Transpl Int.'}, { 'issue': '6', 'key': '10.1111/ajt.16369_bib9', 'doi-asserted-by': 'crossref', 'first-page': '610', 'DOI': '10.1016/j.healun.2020.04.004', 'article-title': 'COVID-19 in a lung transplant recipient', 'volume': '39', 'author': 'Aigner', 'year': '2020', 'journal-title': 'J Heart Lung Transplant.'}, { 'issue': '8', 'key': '10.1111/ajt.16369_bib10', 'doi-asserted-by': 'crossref', 'first-page': '2269', 'DOI': '10.1111/ajt.15947', 'article-title': 'Two distinct cases with COVID-19 in kidney transplant recipients', 'volume': '20', 'author': 'Kim', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib11', 'doi-asserted-by': 'crossref', 'first-page': '1896', 'DOI': '10.1111/ajt.15943', 'article-title': 'Severe COVID-19 in a renal transplant recipient: a focus on ' 'pharmacokinetics', 'volume': '20', 'author': 'Meziyerh', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib12', 'doi-asserted-by': 'crossref', 'first-page': '1902', 'DOI': '10.1111/ajt.15935', 'article-title': 'Covid-19 pneumonia in a kidney transplant recipient successfully ' 'treated with tocilizumab and hydroxychloroquine', 'volume': '20', 'author': 'Fontana', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '6', 'key': '10.1111/ajt.16369_bib13', 'doi-asserted-by': 'crossref', 'first-page': '1076', 'DOI': '10.1016/j.kint.2020.03.018', 'article-title': 'COVID-19 infection in kidney transplant recipients', 'volume': '97', 'author': 'Banerjee', 'year': '2020', 'journal-title': 'Kidney Int.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib14', 'doi-asserted-by': 'crossref', 'first-page': '1819', 'DOI': '10.1111/ajt.15967', 'article-title': 'COVID-19 in kidney transplant recipients', 'volume': '20', 'author': 'Nair', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '6', 'key': '10.1111/ajt.16369_bib15', 'doi-asserted-by': 'crossref', 'first-page': '532', 'DOI': '10.1016/S2468-1253(20)30116-3', 'article-title': 'COVID-19 in long-term liver transplant patients: preliminary experience ' 'from an Italian transplant centre in Lombardy', 'volume': '5', 'author': 'Bhoori', 'year': '2020', 'journal-title': 'Lancet Gastroenterol Hepatol.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib16', 'doi-asserted-by': 'crossref', 'first-page': '1885', 'DOI': '10.1111/ajt.15944', 'article-title': 'Earliest cases of coronavirus disease 2019 (COVID-19) identified in ' 'solid organ transplant recipients in the United States', 'volume': '20', 'author': 'Kates', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib17', 'doi-asserted-by': 'crossref', 'first-page': '1800', 'DOI': '10.1111/ajt.15941', 'article-title': 'COVID-19 in solid organ transplant recipients: initial report from the ' 'US Epicenter', 'volume': '20', 'author': 'Pereira', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib18', 'doi-asserted-by': 'crossref', 'first-page': '1849', 'DOI': '10.1111/ajt.15929', 'article-title': 'COVID-19 in solid organ transplant recipients: a single-center case ' 'series from Spain', 'volume': '20', 'author': 'Fernández-Ruiz', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '25', 'key': '10.1111/ajt.16369_bib19', 'doi-asserted-by': 'crossref', 'first-page': '2475', 'DOI': '10.1056/NEJMc2011117', 'article-title': 'Covid-19 and kidney transplantation', 'volume': '382', 'author': 'Akalin', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'issue': '5', 'key': '10.1111/ajt.16369_bib20', 'doi-asserted-by': 'crossref', 'first-page': '580', 'DOI': '10.1016/j.ekir.2020.04.001', 'article-title': 'Management of patients on dialysis and with kidney transplant during ' 'SARS-COV-2 (COVID-19) pandemic in Brescia, Italy', 'volume': '5', 'author': 'Alberici', 'year': '2020', 'journal-title': 'Kidney Int Rep.'}, { 'issue': '6', 'key': '10.1111/ajt.16369_bib21', 'doi-asserted-by': 'crossref', 'first-page': '748', 'DOI': '10.1016/j.eururo.2020.03.039', 'article-title': 'Coronavirus Disease 2019 pneumonia in immunosuppressed renal transplant ' 'recipients: a summary of 10 confirmed cases in Wuhan, China', 'volume': '77', 'author': 'Zhu', 'year': '2020', 'journal-title': 'Eur Urol.'}, { 'key': '10.1111/ajt.16369_bib22', 'doi-asserted-by': 'crossref', 'unstructured': 'Cravedi P, Mothi Suraj S, Azzi Y, et al. COVID-19 and kidney ' 'transplantation: Results from the TANGO International Transplant ' 'Consortium [published online ahead of print July 10, 2020]. Am J ' 'Transplant. 2020. https://doi.org/10.1111/ajt.16185', 'DOI': '10.1111/ajt.16185'}, { 'key': '10.1111/ajt.16369_bib23', 'doi-asserted-by': 'crossref', 'unstructured': 'Colmenero J, Rodríguez-Perálvarez M, Salcedo M, et al. Epidemiological ' 'pattern, incidence and outcomes of COVID-19 in liver transplant patients ' '[published online ahead of print August 1, 2020]. J Hepatol. ' '2020;S0168–8278(20)30521–3. https://doi.org/10.1016/j.jhep.2020.07.040', 'DOI': '10.1016/j.jhep.2020.07.040'}, { 'key': '10.1111/ajt.16369_bib24', 'doi-asserted-by': 'crossref', 'first-page': '1009', 'DOI': '10.1086/507898', 'article-title': 'A prospective hospital-based study of the clinical impact of non-severe ' 'acute respiratory syndrome (Non-SARS)-related human coronavirus ' 'infection', 'volume': '43', 'author': 'Garbino', 'year': '2006', 'journal-title': 'Clin Infect Dis.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib25', 'doi-asserted-by': 'crossref', 'first-page': '1768', 'DOI': '10.1111/ajt.15832', 'article-title': 'Coronavirus Disease 2019: implications of emerging infections for ' 'transplantation', 'volume': '20', 'author': 'Michaels', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'key': '10.1111/ajt.16369_bib26', 'doi-asserted-by': 'crossref', 'first-page': '977', 'DOI': '10.1034/j.1600-6143.2003.00197.x', 'article-title': 'Severe acute respiratory syndrome (SARS) in a liver transplant ' 'recipient and guidelines for donor SARS screening', 'volume': '3', 'author': 'Kumar', 'year': '2003', 'journal-title': 'Am J Transplant.'}, { 'issue': '4', 'key': '10.1111/ajt.16369_bib27', 'doi-asserted-by': 'crossref', 'first-page': '1101', 'DOI': '10.1111/ajt.13085', 'article-title': 'MERS CoV infection in two renal transplant recipients: case report', 'volume': '15', 'author': 'AlGhamdi', 'year': '2015', 'journal-title': 'Am J Transplant.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib28', 'doi-asserted-by': 'crossref', 'first-page': '1826', 'DOI': '10.1111/ajt.15933', 'article-title': 'Solid organ transplantation programs facing lack of empiric evidence in ' 'the COVID-19 pandemic: a by-proxy society recommendation consensus ' 'approach', 'volume': '20', 'author': 'Ritschl', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '9', 'key': '10.1111/ajt.16369_bib29', 'doi-asserted-by': 'crossref', 'first-page': '2593', 'DOI': '10.1111/ajt.15983', 'article-title': 'COVID-19 in Spain: transplantation in the midst of the pandemic', 'volume': '20', 'author': 'Domínguez-Gil', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'key': '10.1111/ajt.16369_bib30', 'unstructured': 'Coronavirus disease 2019 (COVID-19) and supply of substances of human ' 'origin in the EU/EEA - First update. ' 'https://www.ecdc.europa.eu/en/publications-data/coronavirus-disease-2019-covid-19-and-supply-substances-human-origin. ' 'Accessed August 2020'}, { 'key': '10.1111/ajt.16369_bib31', 'unstructured': 'Rapid risk assessment: Coronavirus disease 2019 (COVID-19) pandemic: ' 'increased transmission in the EU/EEA and the UK – seventh update. ' 'https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-coronavirus-disease-2019-covid-19-pandemic. ' 'Accessed: May 2020'}, { 'issue': '3', 'key': '10.1111/ajt.16369_bib32', 'doi-asserted-by': 'crossref', 'first-page': '272', 'DOI': '10.1016/j.nefro.2020.04.002', 'article-title': 'SARS-CoV-2 infection in patients on renal replacement therapy. Report ' 'of the COVID-19 Registry of the Spanish Society of Nephrology (SEN)', 'volume': '40', 'author': 'Sánchez-Álvarez', 'year': '2020', 'journal-title': 'Nefrología.'}, { 'issue': '3', 'key': '10.1111/ajt.16369_bib33', 'doi-asserted-by': 'crossref', 'first-page': '265', 'DOI': '10.1016/j.nefro.2020.03.002', 'article-title': 'Recommendations on management of the SARS-CoV-2 coronavirus pandemic ' '(Covid-19) in kidney transplant patients', 'volume': '40', 'author': 'López', 'year': '2020', 'journal-title': 'Nefrologia.'}, { 'key': '10.1111/ajt.16369_bib34', 'unstructured': 'Grupo de Trabajo de COVID-19 en el Trasplante de Órgano Sólido ' '(Corona-TOS) Grupo de Estudio de Infección en el Trasplante y el Huésped ' 'Inmunocomprometido (GESITRA-IC) de la Sociedad Española de Enfermedades ' 'Infecciosas y Microbiología Clínica (SEIMC) Red Española de ' 'Investigación en Patología Infecciosa (REIPI) Recomendaciones para el ' 'tratamiento de receptores de TOS con diagnóstico de COVID-19. ' 'https://seimc.org/contenidos/gruposdeestudio/gesitra/documentos/GESITRA-IC_Recomendaciones_COVID-19_en_TOS.pdf. ' 'Accessed August 2020'}, { 'key': '10.1111/ajt.16369_bib35', 'unstructured': 'Comité Científico de la Sociedad Española de Trasplante Hepático (SETH). ' 'Recomendaciones de la SETH frente a la infección COVID-19 en receptores ' 'de trasplante hepático. ' 'https://www.sethepatico.org/docs/2020/Recomend_IMS_COVID_TH.pdf. ' 'Accessed August 2020'}, { 'issue': '8', 'key': '10.1111/ajt.16369_bib36', 'doi-asserted-by': 'crossref', 'first-page': '1929', 'DOI': '10.1111/j.1600-6143.2009.02700.x', 'article-title': 'Donor-derived disease transmission events in the United States: data ' 'reviewed by the OPTN/UNOS Disease Transmission Advisory Committee', 'volume': '9', 'author': 'Ison', 'year': '2009', 'journal-title': 'Am J Transplant.'}, { 'issue': '23', 'key': '10.1111/ajt.16369_bib37', 'first-page': '2526', 'article-title': 'Acute respiratory distress syndrome: the Berlin Definition', 'volume': '307', 'author': 'Ranieri', 'year': '2012', 'journal-title': 'JAMA.'}, { 'issue': '18', 'key': '10.1111/ajt.16369_bib38', 'first-page': '1824', 'article-title': 'Pharmacologic treatments for Coronavirus Disease 2019 (COVID-19): A ' 'review', 'volume': '323', 'author': 'Sanders', 'year': '2020', 'journal-title': 'JAMA.'}, { 'issue': '25', 'key': '10.1111/ajt.16369_bib39', 'doi-asserted-by': 'crossref', 'first-page': '2411', 'DOI': '10.1056/NEJMoa2012410', 'article-title': 'Observational study of hydroxychloroquine in hospitalized patients with ' 'Covid-19', 'volume': '382', 'author': 'Geleris', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib40', 'first-page': '19014', 'article-title': 'Hydroxychloroquine with or without azithromycin in mild-to-moderate ' 'Covid-19 [published online ahead of print July 23, 2020]', 'author': 'Cavalcanti', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib41', 'doi-asserted-by': 'crossref', 'unstructured': 'Skipper CP, Pastick KA, Engen NW, et al. Hydroxychloroquine in ' 'nonhospitalized adults with early COVID-19: A randomized trial ' '[published online ahead of print July 16, 2020]. Ann Intern Med. 2020. ' 'M20–4207. https://doi.org/10.7326/M20-4207', 'DOI': '10.7326/M20-4207'}, { 'key': '10.1111/ajt.16369_bib42', 'doi-asserted-by': 'crossref', 'unstructured': 'Mitjà O, Corbacho-Monne M, Ubals M, et al. Hydroxychloroquine for early ' 'treatment of adults with mild Covid-19: A randomized-controlled trial ' '[published online ahead of print July 16, 2020]. Clin Infect Dis. 2020. ' 'https://doi.org/10.1093/cid/ciaa1009', 'DOI': '10.1093/cid/ciaa1009'}, { 'issue': '19', 'key': '10.1111/ajt.16369_bib43', 'doi-asserted-by': 'crossref', 'first-page': '1787', 'DOI': '10.1056/NEJMoa2001282', 'article-title': 'A trial of lopinavir-ritonavir in adults hospitalized with severe ' 'Covid-19', 'volume': '382', 'author': 'Cao', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib44', 'first-page': '7764', 'article-title': 'Remdesivir for the treatment of Covid-19 - Preliminary report ' '[published online ahead of print May 22, 2020]', 'author': 'Beigel', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib45', 'first-page': '1436', 'article-title': 'Dexamethasone in hospitalized Patients with Covid-19 - Preliminary ' 'report [published online ahead of print July 17, 2020]', 'author': 'Horby', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'key': '10.1111/ajt.16369_bib46', 'doi-asserted-by': 'crossref', 'first-page': '170', 'DOI': '10.3389/fmed.2020.00170', 'article-title': 'Use of corticosteroids in Coronavirus Disease 2019 pneumonia: A ' 'systematic review of the literature', 'volume': '7', 'author': 'Veronese', 'year': '2020', 'journal-title': 'Front Med (Lausanne).'}, { 'issue': '20', 'key': '10.1111/ajt.16369_bib47', 'doi-asserted-by': 'crossref', 'first-page': '10970', 'DOI': '10.1073/pnas.2005615117', 'article-title': 'Effective treatment of severe COVID-19 patients with tocilizumab', 'volume': '117', 'author': 'Xu', 'year': '2020', 'journal-title': 'Proc Natl Acad Sci U S A.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib48', 'doi-asserted-by': 'crossref', 'first-page': '1947', 'DOI': '10.1111/ajt.15905', 'article-title': 'Immunosuppression drug-related and clinical manifestation of ' 'Coronavirus disease 2019: A therapeutical hypothesis', 'volume': '20', 'author': 'Romanelli', 'year': '2020', 'journal-title': 'Am J Transplant.'}, { 'issue': '5', 'key': '10.1111/ajt.16369_bib49', 'doi-asserted-by': 'crossref', 'first-page': '405', 'DOI': '10.1016/j.healun.2020.03.012', 'article-title': 'COVID-19 illness in native and immunosuppressed states: A ' 'clinical-therapeutic staging proposal', 'volume': '39', 'author': 'Siddiqi', 'year': '2020', 'journal-title': 'J Heart Lung Transplant.'}, { 'issue': '18', 'key': '10.1111/ajt.16369_bib50', 'doi-asserted-by': 'crossref', 'first-page': '1708', 'DOI': '10.1056/NEJMoa2002032', 'article-title': 'Clinical characteristics of Coronavirus Disease 2019 in China', 'volume': '382', 'author': 'Guan', 'year': '2020', 'journal-title': 'N Engl J Med.'}, { 'issue': '10241', 'key': '10.1111/ajt.16369_bib51', 'doi-asserted-by': 'crossref', 'first-page': '1907', 'DOI': '10.1016/S0140-6736(20)31187-9', 'article-title': 'Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort ' 'study', 'volume': '395', 'author': 'Kuderer', 'year': '2020', 'journal-title': 'Lancet.'}, { 'key': '10.1111/ajt.16369_bib52', 'doi-asserted-by': 'crossref', 'first-page': '1081', 'DOI': '10.1001/jamainternmed.2020.2033', 'article-title': 'Development and validation of a clinical risk score to predict the ' 'occurrence of critical illness in hospitalized patients with COVID-19', 'volume': '180', 'author': 'Liang', 'year': '2020', 'journal-title': 'JAMA Intern Med.'}, { 'issue': '7', 'key': '10.1111/ajt.16369_bib53', 'doi-asserted-by': 'crossref', 'first-page': '934', 'DOI': '10.1001/jamainternmed.2020.0994', 'article-title': 'Risk factors associated with acute respiratory distress syndrome and ' 'death in patients with coronavirus disease 2019 pneumonia in Wuhan ' 'China', 'volume': '180', 'author': 'Wu', 'year': '2020', 'journal-title': 'JAMA Intern Med.'}], 'container-title': 'American Journal of Transplantation', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16369', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ajt.16369', 'content-type': 'application/xml', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://api.elsevier.com/content/article/PII:S1600613522085458?httpAccept=text/xml', 'content-type': 'text/xml', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://api.elsevier.com/content/article/PII:S1600613522085458?httpAccept=text/plain', 'content-type': 'text/plain', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://onlinelibrary.wiley.com/doi/pdf/10.1111/ajt.16369', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2023, 1, 22]], 'date-time': '2023-01-22T14:43:39Z', 'timestamp': 1674398619000}, 'score': 1, 'resource': {'primary': {'URL': 'https://linkinghub.elsevier.com/retrieve/pii/S1600613522085458'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2021, 5]]}, 'references-count': 53, 'journal-issue': {'issue': '5', 'published-print': {'date-parts': [[2021, 5]]}}, 'alternative-id': ['S1600613522085458'], 'URL': 'http://dx.doi.org/10.1111/ajt.16369', 'relation': {}, 'ISSN': ['1600-6135'], 'subject': ['Pharmacology (medical)', 'Transplantation', 'Immunology and Allergy'], 'container-title-short': 'American Journal of Transplantation', 'published': {'date-parts': [[2021, 5]]}, 'assertion': [ {'value': 'Elsevier', 'name': 'publisher', 'label': 'This article is maintained by'}, { 'value': 'COVID-19 in transplant recipients: The Spanish experience', 'name': 'articletitle', 'label': 'Article Title'}, { 'value': 'American Journal of Transplantation', 'name': 'journaltitle', 'label': 'Journal Title'}, { 'value': 'https://doi.org/10.1111/ajt.16369', 'name': 'articlelink', 'label': 'CrossRef DOI link to publisher maintained version'}, {'value': 'article', 'name': 'content_type', 'label': 'Content Type'}, { 'value': 'Copyright © 2021 American Society of Transplantation & American Society of ' 'Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published ' 'by Elsevier B.V. All rights reserved.', 'name': 'copyright', 'label': 'Copyright'}]}
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit