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All Studies   Meta Analysis   Recent:  
0 0.5 1 1.5 2+ Virological cure at day 10 80% Improvement Relative Risk HCQ  Zhong Nanshan (钟南山) et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 197 patients in China Improved viral clearance with HCQ (p=0.0001) c19hcq.org Zhong Nanshan, March 2020 Favors HCQ Favors control

Efficacy and safety of chloroquine for treatment of COVID-19. An open-label, multi-center, non-randomized trial

Zhong Nanshan (钟南山)
Mar 2020  
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197 patients. CQ effective. Day 10 viral RNA negative 91.4% HCQ versus 57.4% control. Median time to negative test 3 days versus 9 days for control.
risk of no virological cure at day 10, 80.0% lower, RR 0.20, p < 0.001, treatment 5 of 115 (4.3%), control 17 of 82 (20.7%), NNT 6.1, adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Zhong Nanshan (钟南山) et al., 26 Mar 2020, retrospective, China, preprint, 1 author.
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Late treatment
is less effective
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