An observational multi-centric COVID-19 sequelae study among health care workers
Ajay Kumar Shukla, Shubham Atal, Aditya Banerjee, Ratinder Jhaj, Sadasivam Balakrishnan, Preeta Kaur Chugh, Denis Xavier, Atiya Faruqui, Aakanksha Singh, Ramasamy Raveendran, Jayanthi Mathaiyan, Jeevitha Gauthaman, Urwashi I Parmar, Raakhi K Tripathi, Sandhya K Kamat, Niyati Trivedi, Prashant Shah, Janki Chauhan, Harihar Dikshit, Hitesh Mishra, Rajiv Kumar, Dinesh Kumar Badyal, Monika Sharma, Mamta Singla, Bikash Medhi, Ajay Prakash, Rupa Joshi, Nabendu S Chatterjee, Jerin Jose Cherian, Ved Prakash Kamboj, Nilima Kshirsagar
The Lancet Regional Health - Southeast Asia, doi:10.1016/j.lansea.2022.100129
Background India has seen more than 43 million confirmed cases of COVID-19 as of April 2022, with a recovery rate of 98.8%, resulting in a large section of the population including the healthcare workers (HCWs), susceptible to develop post COVID sequelae. This study was carried out to assess the nature and prevalence of medical sequelae following COVID-19 infection, and risk factors, if any. Methods This was an observational, multicenter cross-sectional study conducted at eight tertiary care centers. The consenting participants were HCWs between 12 and 52 weeks post discharge after COVID-19 infection. Data on demographics, medical history, clinical features of COVID-19 and various symptoms of COVID sequelae was collected through specific questionnaire. Finding Mean age of the 679 eligible participants was 31.49 ± 9.54 years. The overall prevalence of COVID sequelae was 30.34%, with fatigue (11.5%) being the most common followed by insomnia (8.5%), difficulty in breathing during activity (6%) and pain in joints (5%). The odds of having any sequelae were significantly higher among participants who had moderate to severe COVID-19 (OR 6.51; 95% CI 3.46-12.23) and lower among males (OR 0.55; 95% CI 0.39-0.76). Besides these, other predictors for having sequelae were age (≥45 years), presence of any
Appendix A. Supplementary data Supplementary data related to this article can be found at https://doi. org/10.1016/j.lansea.2022.100129.
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