Analgesics
Antiandrogens
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
Top
Results
Abstract
All HCQ studies
Meta analysis
 
Feedback
Home
next
study
previous
study
c19hcq.org COVID-19 treatment researchHCQHCQ (more..)
Melatonin Meta
Metformin Meta
Azvudine Meta
Bromhexine Meta Molnupiravir Meta
Budesonide Meta
Colchicine Meta
Conv. Plasma Meta Nigella Sativa Meta
Curcumin Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   

Predictors of COVID-19 severity and outcomes in Indian patients with rheumatic diseases: a prospective cohort study

Mathew et al., Rheumatology Advances in Practice, doi:10.1093/rap/rkad025
Feb 2023  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Mortality 20% Improvement Relative Risk Hospitalization 0% Severe case 40% HCQ for COVID-19  Mathew et al.  Prophylaxis Is pre-exposure prophylaxis with HCQ beneficial for COVID-19? Prospective study of 64 patients in India (April 2020 - October 2021) Lower severe cases with HCQ (not stat. sig., p=0.37) c19hcq.org Mathew et al., Rheumatology Advances i.., Feb 2023 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now with p < 0.00000000001 from 411 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 75 treatments. c19hcq.org
Prospective study of 64 rheumatic disease patients with COVID-19, showing no significant difference in outcomes with HCQ use.
Although the 20% lower mortality is not statistically significant, it is consistent with the significant 26% lower mortality [22‑30%] from meta analysis of the 249 mortality results to date.
risk of death, 20.0% lower, OR 0.80, p = 0.80, treatment 23, control 41, RR approximated with OR.
risk of hospitalization, no change, OR 1.00, p = 0.94, treatment 23, control 41, RR approximated with OR.
risk of severe case, 40.0% lower, OR 0.60, p = 0.37, treatment 23, control 41, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mathew et al., 28 Feb 2023, prospective, India, peer-reviewed, 8 authors, study period April 2020 - October 2021.
This PaperHCQAll
Predictors of COVID-19 severity and outcomes in Indian patients with rheumatic diseases: a prospective cohort study
Dr Jithin Mathew, Siddharth Jain, Terence Susngi, Gsrsnk Naidu, Varun Dhir, Aman Sharma, Sanjay Jain, Shefali Khanna, Dr Siddharth Jain, Dr Shefali K Sharma
doi:10.1093/rap/rkad025/7059537
Objectives: There is dearth of data regarding COVID-19 outcomes amongst rheumatic and musculoskeletal diseases (RMD) patients from South-East-Asia. We report the clinico-demographic profile and identify predictors of COVID-19 outcomes in a large cohort of Indian RMD patients. Methods : This prospective cohort study done at PGIMER, Chandigarh (tertiary care centre in India) included RMD patients affected with COVID-19 between April 2020-October 2021. Demographic and clinico-laboratory details of COVID-19 and underlying RMD were noted. Predictors of mortality, hospitalization, and severe COVID-19 were identified using stepwise multivariable logistic regression. Results: A total of 64 SARS-CoV-2 infected RMD patients [age 41.5 (19-85 years); 46 (72%) females] were included. 18(28%) patients had severe COVID-19. 23 (36%) required respiratory support [11 (17%) required mechanical ventilation]. 36 (56%) patients required hospitalization [median duration of stay 10(1-42) days]; 17 (27%) required intensive care unit (ICU) admission. Presence of comorbidities [OR=4.5(1.4-14.7)] was found to independently predict COVID-19 severity. Comorbidities [OR=10.7(2.5-45.4)] and underlying lupus [OR=7.0(1.2-40.8)] were independently associated with COVID-19-hospitalization. Ongoing rheumatic disease activity [OR=6.8(1.3-35.4)] and underlying diagnosis of lupus [OR=7.1(1.2-42.4)] and systemic sclerosis (SSc) [OR=9.5(1.5-61.8)] were found to be strong independent predictors of mortality. Age, gender, underlying RMD-interstitial lung disease (ILD) and choice of immunosuppressive therapy were not associated with COVID-19 severity or adverse outcomes. Conclusion: Presence of comorbidities was independently associated with COVID-19 severity and hospitalization. Ongoing rheumatic disease activity and presence of lupus or SSc independently predicted mortality. Age, gender, type of immunosuppressive therapy and presence of RMD-ILD did not affect COVID-19 severity or outcomes in Indian RMD patients.
Conflict of Interest: The authors have declared no conflicts of interest
References
Akiyama, Hamdeh, Micic, Sakuraba, Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis, Ann Rheum Dis
Alarcón, Izadi, Duarte-García, Reátegui-Sokolova, Clarke, Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance, Ann Rheum Dis
Alqahtani, Oyelade, Aldhahir, Alghamdi, Almehmadi et al., Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-Analysis. Bhatt GC, PLOS ONE
Andersen, Bates, Rashidi, Olex, Mannon et al., Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative, Lancet Rheumatol
Annamalai, Santhanam, Mohanasundaram, Nambi, Sankaran et al., COVID-19 and Rheumatic Diseases in Tamil Nadu -A multicenter retrospective observational study, Indian J Rheumatol
Bower, Frisell, Giuseppe, Delcoigne, Ahlenius et al., Impact of the COVID-19 pandemic on morbidity and mortality in patients with inflammatory joint diseases and in the general population: a nationwide Swedish cohort study, Ann Rheum Dis
Brenner, Ungaro, Gearry, Kaplan, Kissous-Hunt et al., Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry, Gastroenterology
Conway, Grimshaw, Konig, Putman, Duarte-García et al., SARS-CoV-2 Infection and COVID-19 Outcomes in Rheumatic Diseases: A Systematic Literature Review and Meta-Analysis, Arthritis Rheumatol
Dessie, Zewotir, Mortality-related risk factors of COVID-19: a systematic review and metaanalysis of 42 studies and 423,117 patients, BMC Infect Dis
Drake, Docherty, Harrison, Quint, Adamali et al., Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study, Am J Respir Crit Care Med
Francesconi, Cantini, Profili, Mannoni, Bellini et al., COVID-19 epidemiology in rheumatic diseases in Tuscany: A case-control study, Joint Bone Spine
Gianfrancesco, Hyrich, Al-Adely, Carmona, Danila et al., Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry, Ann Rheum Dis
Gianfrancesco, Leykina, Izadi, Taylor, Sparks et al., Association of Race and Ethnicity With COVID-19 Outcomes in Rheumatic Disease: Data From the COVID-19 Global Rheumatology Alliance Physician Registry, Arthritis Rheumatol
Hasseli, Mueller-Ladner, Hoyer, Krause, Lorenz et al., Older age, comorbidity, glucocorticoid use and disease activity are risk factors for COVID-19 hospitalisation in patients with inflammatory rheumatic and musculoskeletal diseases, RMD Open
Jung, Kim, Kim, Choi, Chung et al., Effect of hydroxychloroquine preexposure on infection with SARS-CoV-2 in rheumatic disease patients: a population-based cohort study, Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis
Lee, Choi, Yang, Lee, Park et al., Interstitial lung disease increases susceptibility to and severity of COVID-19, Eur Respir J
Liang, Guan, Chen, Li, Xu, Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China, Lancet Oncol
Mahil, Dand, Mason, Yiu, Tsakok et al., Factors associated with adverse COVID-19 outcomes in patients with psoriasis-insights from a global registry-based study, J Allergy Clin Immunol
Nuñez, Leon, Mucientes, Rodriguez-Rodriguez, Urgelles et al., Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases, Ann Rheum Dis
Pablos, Galindo, Carmona, Lledó, Retuerto et al., Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study, Ann Rheum Dis
Robinson, Yazdany, Racial and ethnic differences in COVID-19 outcomes: a call to action, Lancet Rheumatol
Salvarani, Mancuso, Gradellini, Viani, Pandolfi et al., Susceptibility to COVID-19 in Patients Treated With Antimalarials: A Population-Based Study in Emilia-Romagna, Northern Italy, Arthritis Rheumatol
Sattui, Conway, Putman, Seet, Gianfrancesco et al., Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance physician registry: a retrospective cohort study, Lancet Rheumatol
Scirè, Carrara, Zanetti, Landolfi, Chighizola et al., COVID-19 in rheumatic diseases in Italy: first results from the Italian registry of the Italian Society for Rheumatology (CONTROL-19), Clin Exp Rheumatol
Scully, Haverfield, Ursin, Tannenbaum, Klein, Considering how biological sex impacts immune responses and COVID-19 outcomes, Nat Rev Immunol
Shin, Shin, Moon, Jin, Kim et al., Autoimmune inflammatory rheumatic diseases and COVID-19 outcomes in South Korea: a nationwide cohort study, Lancet Rheumatol
Shobha, Chanakya, Haridas, Kumar, Chebbi et al., Do all patients with rheumatic Diseases have a higher risk of COVID 19? Initial results from the Karnataka Rheumatology Association COVID 19 Cohort Study (KRACC), Indian J Rheumatol
Silva, Cohen, Mccormick, Zhang, Wallace, COVID-19 Outcomes in Patients With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A US Multicenter, Comparative Cohort Study, Arthritis Rheumatol
Snfmi, Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients, Ann Rheum Dis
Topless, Gaffo, Stamp, Robinson, Dalbeth et al., Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study, Lancet Rheumatol
Wang, Ma, Xu, Liu, Chen et al., Prevalence and risk of COVID-19 in patients with rheumatic diseases: a systematic review and meta-analysis, Clin Rheumatol
Yang, Koh, Moon, Yoo, Ha et al., Allergic disorders and susceptibility to and severity of COVID-19: A nationwide cohort study, J Allergy Clin Immunol
Zanetti, Carrara, Landolfi, Rozza, Chighizola et al., Increased COVID-19 mortality in patients with rheumatic diseases: results from the CONTROL-19 study by the Italian Society for Rheumatology, Clin Exp Rheumatol
{ 'indexed': {'date-parts': [[2023, 3, 27]], 'date-time': '2023-03-27T04:14:37Z', 'timestamp': 1679890477596}, 'reference-count': 36, 'publisher': 'Oxford University Press (OUP)', 'issue': '1', 'license': [ { 'start': { 'date-parts': [[2023, 2, 28]], 'date-time': '2023-02-28T00:00:00Z', 'timestamp': 1677542400000}, 'content-version': 'vor', 'delay-in-days': 60, 'URL': 'https://creativecommons.org/licenses/by/4.0/'}], 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'published-print': {'date-parts': [[2022, 12, 30]]}, 'abstract': '<jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>There is ' 'dearth of data regarding the outcomes of coronavirus disease 2019 (COVID-19) among rheumatic ' 'and musculoskeletal disease (RMD) patients from Southeast Asia. We report the ' 'clinicodemographic profile and identify predictors of COVID-19 outcomes in a large cohort of ' 'Indian RMD ' 'patients.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This ' 'prospective cohort study, carried out at the Postgraduate Institute of Medical Education and ' 'Research, Chandigarh (a tertiary care centre in India), included RMD patients affected with ' 'COVID-19 between April 2020 and October 2021. Demographic and clinical and laboratory details ' 'of COVID-19 and underlying RMD were noted. Predictors of mortality, hospitalization and ' 'severe COVID-19 were identified using stepwise multivariable logistic ' 'regression.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A total of ' '64 severe acute respiratory syndrome coronavirus-2-infected RMD patients [age 41.5 ' '(19–85)\u2009years; 46 (72%) females] were included. Eighteen (28%) patients had severe ' 'COVID-19. Twenty-three (36%) required respiratory support [11 (17%) required mechanical ' 'ventilation]. Thirty-six (56%) patients required hospitalization [median duration of stay 10 ' '(1–42) days]; 17 (27%) required intensive care unit admission. Presence of co-morbidities ' '[odds ratio (OR)\u2009=\u20094.5 (95% CI: 1.4, 14.7)] was found to be an independent ' 'predictor of COVID-19 severity. Co-morbidities [OR\u2009=\u200910.7 (95% CI: 2.5, 45.4)] and ' 'underlying lupus [OR\u2009=\u20097.0 (95% CI: 1.2, 40.8)] were independently associated with ' 'COVID-19 hospitalization. Ongoing rheumatic disease activity [OR\u2009=\u20096.8 (95% CI: ' '1.3, 35.4)] and underlying diagnosis of lupus [OR\u2009=\u20097.1 (95% CI: 1.2, 42.4)] and ' 'SSc [OR\u2009=\u20099.5 (95% CI: 1.5, 61.8)] were found to be strong independent predictors ' 'of mortality. Age, sex, underlying RMD-associated interstitial lung disease and choice of ' 'immunosuppressive therapy were not associated with COVID-19 severity or adverse ' 'outcomes.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>The ' 'presence of co-morbidities was independently associated with COVID-19 severity and ' 'hospitalization. Ongoing rheumatic disease activity and the presence of lupus or SSc ' 'independently predicted mortality. Age, sex, type of immunosuppressive therapy and presence ' 'of RMD-associated interstitial lung disease did not affect COVID-19 severity or outcomes in ' 'Indian RMD patients.</jats:p></jats:sec>', 'DOI': '10.1093/rap/rkad025', 'type': 'journal-article', 'created': {'date-parts': [[2023, 2, 28]], 'date-time': '2023-02-28T12:14:00Z', 'timestamp': 1677586440000}, 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Predictors of COVID-19 severity and outcomes in Indian patients with rheumatic diseases: a ' 'prospective cohort study', 'prefix': '10.1093', 'volume': '7', 'author': [ { 'ORCID': 'http://orcid.org/0000-0001-7043-4654', 'authenticated-orcid': False, 'given': 'Jithin', 'family': 'Mathew', 'sequence': 'first', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'ORCID': 'http://orcid.org/0000-0003-4065-5880', 'authenticated-orcid': False, 'given': 'Siddharth', 'family': 'Jain', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'given': 'Terence', 'family': 'Susngi', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Internal Medicine, Postgraduate Institute of ' 'Medical Education and Research, Chandigarh, India'}]}, { 'ORCID': 'http://orcid.org/0000-0002-9727-044X', 'authenticated-orcid': False, 'given': 'Shankar', 'family': 'Naidu', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'ORCID': 'http://orcid.org/0000-0002-3626-0694', 'authenticated-orcid': False, 'given': 'Varun', 'family': 'Dhir', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'given': 'Aman', 'family': 'Sharma', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'ORCID': 'http://orcid.org/0000-0002-0141-7655', 'authenticated-orcid': False, 'given': 'Sanjay', 'family': 'Jain', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}, { 'ORCID': 'http://orcid.org/0000-0002-8821-6652', 'authenticated-orcid': False, 'given': 'Shefali Khanna', 'family': 'Sharma', 'sequence': 'additional', 'affiliation': [ { 'name': 'Division of Clinical Immunology and Rheumatology, Department of ' 'Internal Medicine, Postgraduate Institute of Medical Education ' 'and Research , Chandigarh, India'}]}], 'member': '286', 'published-online': {'date-parts': [[2023, 2, 28]]}, 'reference': [ {'key': '2023030819251207700_', 'author': 'WHO coronavirus (COVID-19) dashboard'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '48', 'DOI': '10.1002/art.41475', 'article-title': 'Susceptibility to COVID-19 in patients treated with antimalarials: a ' 'population-based study in Emilia-Romagna, Northern Italy', 'volume': '73', 'author': 'Salvarani', 'year': '2021', 'journal-title': 'Arthritis Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '611', 'DOI': '10.1016/j.cmi.2020.12.003', 'article-title': 'Effect of hydroxychloroquine pre-exposure on infection with SARS-CoV-2 ' 'in rheumatic disease patients: a population-based cohort study', 'volume': '27', 'author': 'Jung', 'year': '2021', 'journal-title': 'Clin Microbiol Infect'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '1544', 'DOI': '10.1136/annrheumdis-2020-218296', 'article-title': 'Clinical outcomes of hospitalised patients with COVID-19 and chronic ' 'inflammatory and autoimmune rheumatic diseases: a multicentric matched ' 'cohort study', 'volume': '79', 'author': 'Pablos', 'year': '2020', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e698', 'DOI': '10.1016/S2665-9913(21)00151-X', 'article-title': 'Autoimmune inflammatory rheumatic diseases and COVID-19 outcomes in ' 'South Korea: a nationwide cohort study', 'volume': '3', 'author': 'Shin', 'year': '2021', 'journal-title': 'Lancet Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '766', 'DOI': '10.1002/art.42030', 'article-title': 'SARS–CoV-2 infection and COVID-19 outcomes in rheumatic diseases: a ' 'systematic literature review and meta-analysis', 'volume': '74', 'author': 'Conway', 'year': '2022', 'journal-title': 'Arthritis Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '384', 'DOI': '10.1136/annrheumdis-2020-218946', 'article-title': 'Prevalence and clinical outcomes of COVID-19 in patients with ' 'autoimmune diseases: a systematic review and meta-analysis', 'volume': '80', 'author': 'Akiyama', 'year': '2021', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '859', 'DOI': '10.1136/annrheumdis-2020-217871', 'article-title': 'Characteristics associated with hospitalisation for COVID-19 in people ' 'with rheumatic disease: data from the COVID-19 Global Rheumatology ' 'Alliance physician-reported registry', 'volume': '79', 'author': 'Gianfrancesco', 'year': '2020', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '527', 'DOI': '10.1136/annrheumdis-2020-218310', 'article-title': 'Severity of COVID-19 and survival in patients with rheumatic and ' 'inflammatory diseases: data from the French RMD COVID-19 cohort of 694 ' 'patients', 'volume': '80', 'author': 'FAI2R/SFR/SNFMI/SOFREMIP/CRI/IMIDIATE Consortium and Contributors', 'year': '2021', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e274', 'DOI': '10.1016/S2665-9913(21)00401-X', 'article-title': 'Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a ' 'population-based study', 'volume': '4', 'author': 'Topless', 'year': '2022', 'journal-title': 'Lancet Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '60', 'DOI': '10.1016/j.jaci.2020.10.007', 'article-title': 'Factors associated with adverse COVID-19 outcomes in patients with ' 'psoriasis—insights from a global registry–based study', 'volume': '147', 'author': 'Mahil', 'year': '2021', 'journal-title': 'J Allergy Clin Immunol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '481', 'DOI': '10.1053/j.gastro.2020.05.032', 'article-title': 'Corticosteroids, but not TNF antagonists, are associated with adverse ' 'COVID-19 outcomes in patients with inflammatory bowel diseases: results ' 'from an international registry', 'volume': '159', 'author': 'Brenner', 'year': '2020', 'journal-title': 'Gastroenterology'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e001464', 'DOI': '10.1136/rmdopen-2020-001464', 'article-title': 'Older age, comorbidity, glucocorticoid use and disease activity are ' 'risk factors for COVID-19 hospitalisation in patients with inflammatory ' 'rheumatic and musculoskeletal diseases', 'volume': '7', 'author': 'Hasseli', 'year': '2021', 'journal-title': 'RMD Open'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '374', 'DOI': '10.1002/art.41567', 'article-title': 'Association of race and ethnicity with COVID-19 outcomes in rheumatic ' 'disease: data from the COVID-19 Global Rheumatology Alliance Physician ' 'Registry', 'volume': '73', 'author': 'Gianfrancesco', 'year': '2021', 'journal-title': 'Arthritis Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e455', 'DOI': '10.1016/S2665-9913(22)00135-7', 'article-title': 'Racial and ethnic differences in COVID-19 outcomes: a call to action', 'volume': '4', 'author': 'Robinson', 'year': '2022', 'journal-title': 'Lancet Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '164', 'DOI': '10.4103/injr.injr_261_20', 'article-title': 'Do all patients with rheumatic diseases have a higher risk of COVID 19? ' 'Initial results from the Karnataka Rheumatology Association COVID 19 ' 'Cohort Study (KRACC)', 'volume': '16', 'author': 'Shobha', 'year': '2021', 'journal-title': 'Indian J Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '441', 'DOI': '10.4103/injr.injr_327_20', 'article-title': 'COVID-19 and rheumatic diseases in Tamil Nadu – a multicenter ' 'retrospective observational study', 'volume': '16', 'author': 'Annamalai', 'year': '2021', 'journal-title': 'Indian J Rheumatol'}, {'key': '2023030819251207700_', 'author': 'World Health Organization', 'year': '2021'}, { 'key': '2023030819251207700_', 'author': 'Ministry of Health and Family Welfare, Government of India'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '105131', 'DOI': '10.1016/j.jbspin.2021.105131', 'article-title': 'COVID-19 epidemiology in rheumatic diseases in Tuscany: a case-control ' 'study', 'volume': '88', 'author': 'Francesconi', 'year': '2021', 'journal-title': 'Joint Bone Spine'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '1086', 'DOI': '10.1136/annrheumdis-2021-219845', 'article-title': 'Impact of the COVID-19 pandemic on morbidity and mortality in patients ' 'with inflammatory joint diseases and in the general population: a ' 'nationwide Swedish cohort study', 'volume': '80', 'author': 'Bower', 'year': '2021', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '1393', 'DOI': '10.1136/annrheumdis-2020-217984', 'article-title': 'Risk factors for hospital admissions related to COVID-19 in patients ' 'with autoimmune inflammatory rheumatic diseases', 'volume': '79', 'author': 'Freites Nuñez', 'year': '2020', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '970', 'DOI': '10.1136/annrheumdis-2021-221636', 'article-title': 'Characteristics associated with poor COVID-19 outcomes in individuals ' 'with systemic lupus erythematosus: data from the COVID-19 Global ' 'Rheumatology Alliance', 'volume': '81', 'author': 'Ugarte-Gil', 'year': '2022', 'journal-title': 'Ann Rheum Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e855', 'DOI': '10.1016/S2665-9913(21)00316-7', 'article-title': 'Outcomes of COVID-19 in patients with primary systemic vasculitis or ' 'polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance ' 'physician registry: a retrospective cohort study', 'volume': '3', 'author': 'Sattui', 'year': '2021', 'journal-title': 'Lancet Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '855', 'DOI': '10.1186/s12879-021-06536-3', 'article-title': 'Mortality-related risk factors of COVID-19: a systematic review and ' 'meta-analysis of 42 studies and 423,117 patients', 'volume': '21', 'author': 'Dessie', 'year': '2021', 'journal-title': 'BMC Infect Dis'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '442', 'DOI': '10.1038/s41577-020-0348-8', 'article-title': 'Considering how biological sex impacts immune responses and COVID-19 ' 'outcomes', 'volume': '20', 'author': 'Scully', 'year': '2020', 'journal-title': 'Nat Rev Immunol'}, { 'key': '2023030819251207700_', 'first-page': '748', 'article-title': 'COVID-19 in rheumatic diseases in Italy: first results from the Italian ' 'registry of the Italian Society for Rheumatology (CONTROL-19)', 'volume': '38', 'author': 'Scirè', 'year': '2020', 'journal-title': 'Clin Exp Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '2213', 'DOI': '10.1007/s10067-022-06087-1', 'article-title': 'Prevalence and risk of COVID-19 in patients with rheumatic diseases: a ' 'systematic review and meta-analysis', 'volume': '41', 'author': 'Wang', 'year': '2022', 'journal-title': 'Clin Rheumatol'}, { 'key': '2023030819251207700_', 'first-page': '2038', 'article-title': 'Increased COVID-19 mortality in patients with rheumatic diseases: ' 'results from the CONTROL-19 study by the Italian Society for ' 'Rheumatology', 'volume': '40', 'author': 'Zanetti', 'year': '2022', 'journal-title': 'Clin Exp Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '914', 'DOI': '10.1002/art.41619', 'article-title': 'COVID-19 outcomes in patients with systemic autoimmune rheumatic ' 'diseases compared to the general population: a US multicenter, ' 'comparative cohort study', 'volume': '73', 'author': 'D’Silva', 'year': '2021', 'journal-title': 'Arthritis Rheumatol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e0233147', 'DOI': '10.1371/journal.pone.0233147', 'article-title': 'Prevalence, severity and mortality associated with COPD and smoking in ' 'patients with COVID-19: a rapid systematic review and meta-analysis', 'volume': '15', 'author': 'Alqahtani', 'year': '2020', 'journal-title': 'PLoS ONE'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '335', 'DOI': '10.1016/S1470-2045(20)30096-6', 'article-title': 'Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China', 'volume': '21', 'author': 'Liang', 'year': '2020', 'journal-title': 'Lancet Oncol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '790', 'DOI': '10.1016/j.jaci.2020.08.008', 'article-title': 'Allergic disorders and susceptibility to and severity of COVID-19: a ' 'nationwide cohort study', 'volume': '146', 'author': 'Yang', 'year': '2020', 'journal-title': 'J Allergy Clin Immunol'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '2004125', 'DOI': '10.1183/13993003.04125-2020', 'article-title': 'Interstitial lung disease increases susceptibility to and severity of ' 'COVID-19', 'volume': '58', 'author': 'Lee', 'year': '2021', 'journal-title': 'Eur Respir J'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': '1656', 'DOI': '10.1164/rccm.202007-2794OC', 'article-title': 'Outcome of hospitalization for COVID-19 in patients with interstitial ' 'lung disease. An international multicenter study', 'volume': '202', 'author': 'Drake', 'year': '2020', 'journal-title': 'Am J Respir Crit Care Med'}, { 'key': '2023030819251207700_', 'doi-asserted-by': 'crossref', 'first-page': 'e33', 'DOI': '10.1016/S2665-9913(21)00325-8', 'article-title': 'Long-term use of immunosuppressive medicines and in-hospital COVID-19 ' 'outcomes: a retrospective cohort study using data from the National ' 'COVID Cohort Collaborative', 'volume': '4', 'author': 'Andersen', 'year': '2022', 'journal-title': 'Lancet Rheumatol'}], 'container-title': 'Rheumatology Advances in Practice', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://academic.oup.com/rheumap/advance-article-pdf/doi/10.1093/rap/rkad025/49350397/rkad025.pdf', 'content-type': 'application/pdf', 'content-version': 'am', 'intended-application': 'syndication'}, { 'URL': 'https://academic.oup.com/rheumap/article-pdf/7/1/rkad025/49457343/rkad025.pdf', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'syndication'}, { 'URL': 'https://academic.oup.com/rheumap/article-pdf/7/1/rkad025/49457343/rkad025.pdf', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2023, 3, 26]], 'date-time': '2023-03-26T20:42:03Z', 'timestamp': 1679863323000}, 'score': 1, 'resource': { 'primary': { 'URL': 'https://academic.oup.com/rheumap/article/doi/10.1093/rap/rkad025/7059537'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2022, 12, 30]]}, 'references-count': 36, 'journal-issue': {'issue': '1', 'published-print': {'date-parts': [[2022, 12, 30]]}}, 'URL': 'http://dx.doi.org/10.1093/rap/rkad025', 'relation': {}, 'ISSN': ['2514-1775'], 'subject': ['Rheumatology'], 'published-other': {'date-parts': [[2023, 1, 1]]}, 'published': {'date-parts': [[2022, 12, 30]]}}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit