Abstract: PLOS ONE RESEARCH ARTICLE Use of glucocorticoids megadoses in SARSCoV-2 infection in a spanish registry: SEMICOVID-19 a1111111111 a1111111111 a1111111111 a1111111111 a1111111111 OPEN ACCESS Citation: Lavilla Olleros C, Ausı́n Garcı́a C, Bendala Estrada AD, Muñoz A, Wikman Jogersen PE, Fernández Cruz A, et al. (2022) Use of glucocorticoids megadoses in SARS-CoV-2 infection in a spanish registry: SEMI-COVID-19. PLoS ONE 17(1): e0261711. https://doi.org/ 10.1371/journal.pone.0261711 Editor: Aleksandar R. Zivkovic, Heidelberg University Hospital, GERMANY Received: July 4, 2021 Accepted: December 7, 2021 Cristina Lavilla Olleros ID1☯*, Cristina Ausı́n Garcı́a1☯, Alejandro David Bendala Estrada1☯, Ana Muñoz2, Philip Erick Wikman Jogersen ID3, Ana Fernández Cruz4, Vicente Giner Galvañ3, Juan Antonio Vargas4, José Miguel Seguı́ Ripoll3, Manuel Rubio-Rivas5, Rodrigo Miranda Godoy6, Luis Mérida Rodrigo7, Eva Fonseca Aizpuru ID8, Francisco Arnalich Fernández9, Arturo Artero10, Jose Loureiro Amigo11, Gema Marı́a Garcı́a Garcı́a ID12, Luis Corral Gudino ID13, Jose Jiménez Torres ID14, JoséManuel Casas-Rojo15‡, Jesús Millán Núñez-Cortés1‡, On behalf of the SEMI-COVID-19 Network¶ 1 General Internal Medicine Department, Hospital Universitario Gregorio Marañón, Madrid, Spain, 2 General Internal Medicine Department, Infanta Cristina Hospital: Hospital Universitario Infanta 2 Cristina, ParlaMadrid, Spain, 3 General Internal Medicine Department, Hospital Universitario San Juan de Alicante, San Juan de Alicante-Alicante, Spain, 4 General Internal Medicine Department, Hospital Universitario Puerta de Hierro, Madrid, Spain, 5 General Internal Medicine Department, H. Univ. de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain, 6 General Internal Medicine Department, 12th of October University Hospital: Hospital Universitario 12 de Octubre, Madrid, Spain, 7 General Internal Medicine Department, Hospital Costa del Sol, Málaga, Spain, 8 General Internal Medicine Department, Hospital de Cabueñes: Hospital de Cabuenes, Gijón, Spain, 9 General Internal Medicine Department, La Paz University Hospital: Hospital Universitario La Paz, Madrid, Spain, 10 General Internal Medicine Department, Hospital Universitario Dr Peset: Hospital Universitario Doctor Peset, Valencia, Spain, 11 General Internal Medicine Department, Hospital de Sant Joan Despı́ Moisès Broggi: Hospital de Sant Joan Despi Moises Broggi, Barcelona, Spain, 12 General Internal Medicine Department, University Hospital Complex Badajoz: Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, 13 Hospital Universitario Rio Ortega, Valladolid, Spain, 14 General Internal Medicine Department, Hospital Reina Sofı́a: Hospital Reina Sofia, Córdoba, Madrid, Spain, 15 General Internal Medicine Department, Infanta Cristina Hospital: Hospital Universitario Infanta Cristina, Parla-Madrid, Spain ☯ These authors contributed equally to this work. ‡ These authors also contributed equally to this work. ¶ Membership of the SEMI-COVID-19 Network is provided in the Acknowledgments. * cristinalavillaolleros@gmail.com Published: January 21, 2022 Peer Review History: PLOS recognizes the benefits of transparency in the peer review process; therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. The editorial history of this article is available here: https://doi.org/10.1371/journal.pone.0261711 Copyright: © 2022 Lavilla Olleros et..