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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 32% Improvement Relative Risk c19hcq.org Lambermont et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Predictors of Mortality and Effect of Drug Therapies in Mechanically Ventilated Patients With Coronavirus Disease 2019: A Multicenter Cohort Study
Lambermont et al., Critical Care Explorations, doi:10.1097/CCE.0000000000000305
28 Nov 2020    Source   PDF   Share   Tweet
Retrospective 247 mechanically ventilated patients showing lower mortality with HCQ, but not statistically significant on multiple Cox regression.
The paper gives the p value for multiple Cox (0.46) and simple Cox (0.02), but does not specify the adjusted risk values.
Although the 32% lower mortality is not statistically significant, it is consistent with the significant 22% lower mortality [18‑27%] from meta analysis of the 228 mortality results to date.
risk of death, 32.3% lower, RR 0.68, p = 0.46, treatment 97 of 225 (43.1%), control 14 of 22 (63.6%), NNT 4.9, adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lambermont et al., 28 Nov 2020, retrospective, Belgium, peer-reviewed, 15 authors.
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This PaperHCQAll
Late treatment
is less effective
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