Retrospective 152 mechanically ventilated patients in the USA showing unadjusted lower mortality with vitamin C, vitamin D, HCQ, and zinc treatment, statistically significant only for vitamin C.
Although the 20% lower mortality is not statistically significant, it is consistent with the significant 24% lower mortality [19‑28%]
from meta analysis of the 246 mortality results to date
This study is excluded in the after exclusion results of meta
unadjusted results with no group details.
risk of death, 20.4% lower, RR 0.80, p = 0.48, treatment 86 of 144 (59.7%), control 6 of 8 (75.0%), NNT 6.5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Krishnan et al., 20 Jul 2020, retrospective, USA, peer-reviewed, 13 authors, dosage not specified.
Clinical comorbidities, characteristics, and outcomes of mechanically ventilated patients in the State of Michigan with SARS-CoV-2 pneumonia
Journal of Clinical Anesthesia, doi:10.1016/j.jclinane.2020.110005
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