Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19hcq.org COVID-19 treatment researchHCQHCQ (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis       

Prevalence and clinical correlates of COVID-19 outbreak among healthcare workers in a tertiary level hospital

Khurana et al., medRxiv, doi:10.1101/2020.07.21.20159301
Jul 2020  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Case 51% Improvement Relative Risk HCQ for COVID-19  Khurana et al.  Prophylaxis Is pre-exposure prophylaxis with HCQ beneficial for COVID-19? Retrospective 181 patients in India Fewer cases with HCQ (p=0.021) c19hcq.org Khurana et al., medRxiv, July 2020 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020, now with p < 0.00000000001 from 419 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19hcq.org
Study of hospital health care workers showing HCQ prophylaxis reduces COVID-19 significantly, OR 0.30, p=0.02. 94 positive health care workers with a matched sample of 87 testing negative. Full course prophylaxis was important in this study which used a low dose of 400mg/week HCQ (800mg for week 1), so it may take longer to reach therapeutic levels. Actual benefit of HCQ may be larger because severity of symptoms are not considered here but HCQ may also reduce severity.
risk of case, 51.0% lower, RR 0.49, p = 0.02, treatment 6 of 22 (27.3%), control 88 of 159 (55.3%), NNT 3.6, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Khurana et al., 24 Jul 2020, retrospective, India, preprint, survey, 6 authors.
This PaperHCQAll
Prevalence and clinical correlates of COVID-19 outbreak among health care workers in a tertiary level hospital in Delhi
Dr Ankit Khurana, G P Kaushal, Rishi Gupta, Vansh Verma, Kabir Sharma, Manmohan Kohli
doi:10.1101/2020.07.21.20159301
In this study, we summarize the epidemiological characteristics of COVID-19 outbreak among Healthcare workers (HCWs) in a tertiary care hospital and compared various parameters and preventive measures taken by positive HCWs to a comparable cohort of COVID negative HCWs. 52.1% of COVID-19 positive HCWs showed symptoms of which only three needed hospitalization possibly due to a younger cohort of HCWs who got infected (35.9 ± 9.3 years). Findings of present study found some protective role of full course prophylactic hydroxychloroquine as compared to a control group (p=0.021) and use of N95 masks over others (p<0.001). Our results did not show any added protection with the use of prophylactic Vitamin C, D, Zinc, or betadine gargles. We also observed outbreak control with increased awareness, near universal testing, PPE provision, sanitization drive, and promoting social distancing among HCWs. .
References
Arons, Hatfield, Reddy, Kimball, James et al., Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility, N Engl J Med
Baggett, Keyes, Sporn, Gaeta, COVID-19 outbreak at a large homeless shelter in Boston: Implications for universal testing, Public and Global Health, doi:10.1101/2020.04.12.20059618
Bai, Yao, Wei, Tian, Jin et al., Presumed Asymptomatic Carrier Transmission of COVID-19, JAMA
Chen Jun, Liu Danping, Li, Liu Ping, Xu Qingnian et al., A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19, J Zhejiang Univ (Med Sci)
Chen, Hu, Zhang, Jiang, Han et al., Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial, Epidemiology
Cheng, Jian, Liu, Ng, Huang et al., Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset, JAMA Intern Med
Du, Xu, Wu, Wang, Cowling et al., Serial Interval of COVID-19 among Publicly Reported Confirmed Cases, Emerging Infect Dis
Fang, Nie, Penny, Transmission dynamics of the COVID 19 outbreak and effectiveness of government interventions: A data driven analysis, J Med Virol
Ferretti, Wymant, Kendall, Zhao, Nurtay et al., Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing, Science
Gao, Tian, Yang, Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies, Biosci Trends
Gautret, Lagier, Parola, Hoang, Meddeb et al., Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study, Travel Medicine and Infectious Disease
Gautret, Lagier, Parola, Hoang, Meddeb et al., Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial, International Journal of Antimicrobial Agents
Guan, Ni, Hu, Liang, Ou et al., Clinical Characteristics of Coronavirus Disease 2019 in China, N Engl J Med
Gudbjartsson, Helgason, Jonsson, Magnusson, Melsted et al., Spread of SARS-CoV-2 in the Icelandic Population, N Engl J Med
He, Lau, Wu, Deng, Wang et al., Temporal dynamics in viral shedding and transmissibility of COVID-19, Nat Med
Hu, Song, Xu, Chen, Xu, Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China, Sci China Life Sci
Huang, Wang, Li, Ren, Zhao et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet
Lauer, Grantz, Bi, Jones, Zheng et al., The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application, Annals of Internal Medicine
Lavezzo, Franchin, Ciavarella, Cuomo-Dannenburg, Barzon et al., Suppression of COVID-19 outbreak in the municipality of Vo, Italy [Internet, Epidemiology, doi:10.1101/2020.04.17.20053157
Leung, Chu, Shiu, Chan, Mcdevitt et al., Respiratory virus shedding in exhaled breath and efficacy of face masks, Nat Med
Li, Pei, Chen, Song, Zhang et al., Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2), Science
Liang, Wu, There may be virus in conjunctival secretion of patients with COVID-19, Acta Ophthalmol
Liu, Ning, Chen, Guo, Liu et al., Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals, Nature
Liu, Yan, Xiang, Liu, Viral dynamics in mild and severe cases of COVID-19, Lancet Infect Dis
Magagnoli, Narendran, Pereira, Cummings, Hardin et al., Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19
Mahevas, Tran, Roumier, Chabrol, Paule et al., No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial, doi:10.1101/2020.04.10.20060699
Mcmichael, Clark, Pogosjans, Kay, Lewis et al., COVID-19 in a Long-Term Care Facility -King County, Washington, MMWR Morb Mortal Wkly Rep
Mizumoto, Kagaya, Zarebski, Chowell, Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Euro Surveill
Moriarty, Plucinski, Marston, Kurbatova, Knust et al., Public Health Responses to COVID-19 Outbreaks on Cruise Ships -Worldwide, February, MMWR Morb Mortal Wkly Rep
Ong, Tan, Chia, Lee, Ng et al., Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient, JAMA
Pan, Chen, Xia, Wu, Li et al., Asymptomatic cases in a family cluster with SARS-CoV-2 infection, Lancet Infect Dis
Pan, Mu, Yang, Sun, Wang et al., Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study, Am J Gastroenterol
Pan, Zhang, Yang, Poon, Wang, Viral load of SARS-CoV-2 in clinical samples, Lancet Infect Dis
Qian, Yang, Ma, Wang, Li et al., A COVID-19 Transmission within a family cluster by presymptomatic infectors in China, Clin Infect Dis
Radonovich, Simberkoff, Bessesen, Brown, Cummings et al., N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial, JAMA
Reinhard, Ikonomidis, Broome, Gorostidi, Anosmia and COVID-19
Siddiqi, Mehra, COVID-19 illness in native and immunosuppressed states: A clinicaltherapeutic staging proposal, J Heart Lung Transplant
Sutton, Fuchs, 'alton, Goffman, Universal Screening for SARS-CoV-2 in Women Admitted for Delivery, N Engl J Med
Tang, Cao, Han, Wang, Chen et al., Hydroxychloroquine in patients mainly with mild to moderate COVID-19: an open-label, randomized, controlled trial
To, Tsang, Leung, Tam, Wu et al., Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study, Lancet Infect Dis
Van Doremalen, Bushmaker, Morris, Holbrook, Gamble et al., Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1, N Engl J Med
Wang, Cao, Zhang, Yang, Liu et al., Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro, Cell Res
Wang, Liu, Liu, Wang, Luo et al., Clinical Outcomes in 55 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Who Were Asymptomatic at Hospital Admission in Shenzhen, China, The Journal of Infectious Diseases
Wang, Xu, Gao, Lu, Han et al., Detection of SARS-CoV-2 in Different Types of Clinical Specimens, JAMA
Woelfel, Corman, Guggemos, Seilmaier, Zange et al., Clinical presentation and virological assessment of hospitalized cases of coronavirus disease 2019 in a travel-associated transmission cluster
Wu, Nethery, Sabath, Braun, Dominici, Exposure to air pollution and COVID-19 mortality in the United States: A nationwide cross-sectional study, Epidemiology, doi:10.1101/2020.04.05.20054502
Xiao, Tong, Zhang, Profile of RT-PCR for SARS-CoV-2: a preliminary study from 56 COVID-19 patients, Clin Infect Dis
Zhou, Yu, Du, Fan, Liu et al., Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study, Lancet
Zou, Ruan, Huang, Liang, Huang et al., SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients, N Engl J Med
{ 'institution': [{'name': 'medRxiv'}], 'indexed': { 'date-parts': [[2023, 11, 16]], 'date-time': '2023-11-16T19:24:38Z', 'timestamp': 1700162678654}, 'posted': {'date-parts': [[2020, 7, 24]]}, 'group-title': 'Public and Global Health', 'reference-count': 51, 'publisher': 'Cold Spring Harbor Laboratory', 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'accepted': {'date-parts': [[2020, 7, 24]]}, 'abstract': '<jats:title>Abstract</jats:title><jats:p>In this study, we summarize the epidemiological ' 'characteristics of COVID-19 outbreak among Healthcare workers (HCWs) in a tertiary care ' 'hospital and compared various parameters and preventive measures taken by positive HCWs to a ' 'comparable cohort of COVID negative HCWs. 52.1% of COVID-19 positive HCWs showed symptoms of ' 'which only three needed hospitalization possibly due to a younger cohort of HCWs who got ' 'infected (35.9 ± 9.3 years). Findings of present study found some protective role of full ' 'course prophylactic hydroxychloroquine as compared to a control group (p=0.021) and use of ' 'N95 masks over others (p&lt;0.001). Our results did not show any added protection with the ' 'use of prophylactic Vitamin C, D, Zinc, or betadine gargles. We also observed outbreak ' 'control with increased awareness, near universal testing, PPE provision, sanitization drive, ' 'and promoting social distancing among HCWs.</jats:p>', 'DOI': '10.1101/2020.07.21.20159301', 'type': 'posted-content', 'created': {'date-parts': [[2020, 7, 24]], 'date-time': '2020-07-24T14:12:47Z', 'timestamp': 1595599967000}, 'source': 'Crossref', 'is-referenced-by-count': 9, 'title': 'Prevalence and clinical correlates of COVID-19 outbreak among health care workers in a tertiary ' 'level hospital in Delhi', 'prefix': '10.1101', 'author': [ { 'ORCID': 'http://orcid.org/0000-0001-8397-6903', 'authenticated-orcid': False, 'given': 'Ankit', 'family': 'Khurana', 'sequence': 'first', 'affiliation': []}, {'given': 'GP', 'family': 'Kaushal', 'sequence': 'additional', 'affiliation': []}, {'given': 'Rishi', 'family': 'Gupta', 'sequence': 'additional', 'affiliation': []}, {'given': 'Vansh', 'family': 'Verma', 'sequence': 'additional', 'affiliation': []}, {'given': 'Kabir', 'family': 'Sharma', 'sequence': 'additional', 'affiliation': []}, {'given': 'Manmohan', 'family': 'Kohli', 'sequence': 'additional', 'affiliation': []}], 'member': '246', 'reference': [ { 'key': '2021012000000899000_2020.07.21.20159301v1.1', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMc2004973'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.2', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jama.2020.3227'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.3', 'doi-asserted-by': 'publisher', 'DOI': '10.7326/M20-0504'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.4', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMc2001737'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.5', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S1473-3099(20)30113-4'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.6', 'doi-asserted-by': 'crossref', 'unstructured': 'Wang W , Xu Y , Gao R , Lu R , Han K , Wu G , et al. Detection of ' 'SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020 Mar 11;', 'DOI': '10.1001/jama.2020.3786'}, { 'issue': '3', 'key': '2021012000000899000_2020.07.21.20159301v1.7', 'doi-asserted-by': 'crossref', 'first-page': '223', 'DOI': '10.1111/aos.14413', 'article-title': 'There may be virus in conjunctival secretion of patients with COVID-19', 'volume': '98', 'year': '2020', 'journal-title': 'Acta Ophthalmol'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.8', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S1473-3099(20)30196-1'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.9', 'doi-asserted-by': 'crossref', 'unstructured': 'Woelfel R , Corman VM , Guggemos W , Seilmaier M , Zange S , Mueller MA ' ', et al. Clinical presentation and virological assessment of ' 'hospitalized cases of coronavirus disease 2019 in a travel-associated ' 'transmission cluster [Internet]. Infectious Diseases (except HIV/AIDS); ' '2020 Mar [cited 2020 May 27]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.03.05.20030502', 'DOI': '10.1101/2020.03.05.20030502'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.10', 'doi-asserted-by': 'crossref', 'unstructured': 'Liu Y , Yan L-M , Wan L , Xiang T-X , Le A , Liu J-M , et al. Viral ' 'dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020 ' 'Mar 19;', 'DOI': '10.1016/S1473-3099(20)30232-2'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.11', 'author': 'D C, M T, F R, V D, M A, P P', 'year': '2020', 'journal-title': 'The early phase of the COVID-19 outbreak in Lombardy, Italy'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.12', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/infdis/jiaa119'}, { 'issue': '5', 'key': '2021012000000899000_2020.07.21.20159301v1.13', 'doi-asserted-by': 'crossref', 'first-page': '706', 'DOI': '10.1007/s11427-020-1661-4', 'article-title': 'Clinical characteristics of 24 asymptomatic infections with COVID-19 ' 'screened among close contacts in Nanjing, China', 'volume': '63', 'year': '2020', 'journal-title': 'Sci China Life Sci'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.14', 'doi-asserted-by': 'crossref', 'unstructured': 'Mizumoto K , Kagaya K , Zarebski A , Chowell G. Estimating the ' 'asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on ' 'board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro ' 'Surveill. 2020;25(10).', 'DOI': '10.2807/1560-7917.ES.2020.25.10.2000180'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.15', 'doi-asserted-by': 'crossref', 'unstructured': 'Bai Y , Yao L , Wei T , Tian F , Jin D-Y , Chen L , et al. Presumed ' 'Asymptomatic Carrier Transmission of COVID-19. JAMA. 2020 Feb 21;', 'DOI': '10.1001/jama.2020.2565'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.16', 'doi-asserted-by': 'crossref', 'unstructured': 'Qian G , Yang N , Ma AHY , Wang L , Li G , Chen X , et al. A COVID-19 ' 'Transmission within a family cluster by presymptomatic infectors in ' 'China. Clin Infect Dis. 2020 Mar 23;', 'DOI': '10.1093/cid/ciaa316'}, { 'issue': '6', 'key': '2021012000000899000_2020.07.21.20159301v1.17', 'doi-asserted-by': 'crossref', 'first-page': '1341', 'DOI': '10.3201/eid2606.200357', 'article-title': 'Serial Interval of COVID-19 among Publicly Reported Confirmed Cases', 'volume': '26', 'year': '2020', 'journal-title': 'Emerging Infect Dis'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.18', 'doi-asserted-by': 'publisher', 'DOI': '10.1126/science.abb3221'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.19', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30566-3'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.20', 'doi-asserted-by': 'publisher', 'DOI': '10.7326/M20-3012'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.21', 'doi-asserted-by': 'crossref', 'unstructured': 'Ferretti L , Wymant C , Kendall M , Zhao L , Nurtay A , Abeler-Dörner L ' ', et al. Quantifying SARS-CoV-2 transmission suggests epidemic control ' 'with digital contact tracing. Science. 2020 08;368(6491).', 'DOI': '10.1126/science.abb6936'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.22', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30183-5'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.23', 'doi-asserted-by': 'crossref', 'unstructured': 'Xiao AT , Tong YX , Zhang S. Profile of RT-PCR for SARS-CoV-2: a ' 'preliminary study from 56 COVID-19 patients. Clin Infect Dis. 2020 Apr ' '19;', 'DOI': '10.1093/cid/ciaa460'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.24', 'doi-asserted-by': 'crossref', 'unstructured': 'Cheng H-Y , Jian S-W , Liu D-P , Ng T-C , Huang W-T , Lin H-H , et al. ' 'Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan ' 'and Risk at Different Exposure Periods Before and After Symptom Onset. ' 'JAMA Intern Med [Internet]. 2020 May 1 [cited 2020 May 28]; Available ' 'from: ' 'https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2765641', 'DOI': '10.1001/jamainternmed.2020.2020'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.25', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2008457'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.26', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.healun.2020.03.012'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.27', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S1473-3099(20)30114-6'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.28', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2002032'}, { 'issue': '5', 'key': '2021012000000899000_2020.07.21.20159301v1.29', 'doi-asserted-by': 'crossref', 'first-page': '766', 'DOI': '10.14309/ajg.0000000000000620', 'article-title': 'Clinical Characteristics of COVID-19 Patients With Digestive Symptoms ' 'in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study', 'volume': '115', 'year': '2020', 'journal-title': 'Am J Gastroenterol'}, { 'issue': 'N° 691-2', 'key': '2021012000000899000_2020.07.21.20159301v1.30', 'first-page': '849', 'volume': '16', 'year': '2020', 'journal-title': '[Anosmia and COVID-19]. Rev Med Suisse'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.31', 'doi-asserted-by': 'crossref', 'unstructured': 'Wu X , Nethery RC , Sabath BM , Braun D , Dominici F. Exposure to air ' 'pollution and COVID-19 mortality in the United States: A nationwide ' 'cross-sectional study [Internet]. Epidemiology; 2020 Apr [cited 2020 May ' '28]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.05.20054502', 'DOI': '10.1101/2020.04.05.20054502'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.32', 'unstructured': 'ICMR. National Taskforce for COVID-19. Advisory on the use of ' 'hydroxy-chloroquine as prophylaxis for SARS-CoV-2 infection. 2020. ' '[Internet]. Available from: ' 'https://www.mohfw.gov.in/pdf/AdvisoryontheuseofHydroxychloroquinasprophylaxisforSARSCoV2infection.pdf'}, { 'issue': '2', 'key': '2021012000000899000_2020.07.21.20159301v1.33', 'first-page': '215', 'article-title': 'A pilot study of hydroxychloroquine in treatment of patients with ' 'moderate COVID-19', 'volume': '49', 'year': '2020', 'journal-title': 'J Zhejiang Univ (Med Sci)'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.34', 'doi-asserted-by': 'publisher', 'DOI': '10.5582/bst.2020.01047'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.35', 'doi-asserted-by': 'publisher', 'DOI': '10.1038/s41422-020-0282-0'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.36', 'doi-asserted-by': 'crossref', 'unstructured': 'Chen Z , Hu J , Zhang Z , Jiang S , Han S , Yan D , et al. Efficacy of ' 'hydroxychloroquine in patients with COVID-19: results of a randomized ' 'clinical trial [Internet]. Epidemiology; 2020 Mar [cited 2020 May 28]. ' 'Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.03.22.20040758', 'DOI': '10.1101/2020.03.22.20040758'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.37', 'doi-asserted-by': 'crossref', 'unstructured': 'Gautret P , Lagier J-C , Parola P , Hoang VT , Meddeb L , Mailhe M , et ' 'al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: ' 'results of an open-label non-randomized clinical trial. International ' 'Journal of Antimicrobial Agents. 2020 Mar;105949.', 'DOI': '10.1016/j.ijantimicag.2020.105949'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.38', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.tmaid.2020.101663'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.39', 'doi-asserted-by': 'crossref', 'unstructured': 'Mahevas M , Tran V-T , Roumier M , Chabrol A , Paule R , Guillaud C , et ' 'al. No evidence of clinical efficacy of hydroxychloroquine in patients ' 'hospitalized for COVID-19 infection with oxygen requirement: results of ' 'a study using routinely collected data to emulate a target trial ' '[Internet]. Infectious Diseases (except HIV/AIDS); 2020 Apr [cited 2020 ' 'May 28]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.10.20060699', 'DOI': '10.1101/2020.04.10.20060699'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.40', 'doi-asserted-by': 'crossref', 'unstructured': 'Tang W , Cao Z , Han M , Wang Z , Chen J , Sun W , et al. ' 'Hydroxychloroquine in patients mainly with mild to moderate COVID-19: an ' 'open-label, randomized, controlled trial [Internet]. Public and Global ' 'Health; 2020 Apr [cited 2020 May 28]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.10.20060558', 'DOI': '10.1101/2020.04.10.20060558'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.41', 'doi-asserted-by': 'crossref', 'unstructured': 'Magagnoli J , Narendran S , Pereira F , Cummings T , Hardin JW , Sutton ' 'SS , et al. Outcomes of hydroxychloroquine usage in United States ' 'veterans hospitalized with Covid-19 [Internet]. Infectious Diseases ' '(except HIV/AIDS); 2020 Apr [cited 2020 May 28]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.16.20065920', 'DOI': '10.1101/2020.04.16.20065920'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.42', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jama.2019.11645'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.43', 'doi-asserted-by': 'publisher', 'DOI': '10.1038/s41591-020-0843-2'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.44', 'doi-asserted-by': 'publisher', 'DOI': '10.15585/mmwr.mm6912e1'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.45', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/jmv.25750'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.46', 'doi-asserted-by': 'crossref', 'unstructured': 'Gudbjartsson DF , Helgason A , Jonsson H , Magnusson OT , Melsted P , ' 'Norddahl GL , et al. Spread of SARS-CoV-2 in the Icelandic Population. N ' 'Engl J Med. 2020 Apr 14;NEJMoa2006100.', 'DOI': '10.1101/2020.03.26.20044446'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.47', 'doi-asserted-by': 'crossref', 'unstructured': 'Lavezzo E , Franchin E , Ciavarella C , Cuomo-Dannenburg G , Barzon L , ' 'Del Vecchio C , et al. Suppression of COVID-19 outbreak in the ' 'municipality of Vo, Italy [Internet]. Epidemiology; 2020 Apr [cited 2020 ' 'May 28]. Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.17.20053157', 'DOI': '10.1101/2020.04.17.20053157'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.48', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMc2009316 [published Online First: 2020/04/14]'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.49', 'doi-asserted-by': 'crossref', 'unstructured': 'Baggett TP , Keyes H , Sporn N , Gaeta JM . COVID-19 outbreak at a large ' 'homeless shelter in Boston: Implications for universal testing ' '[Internet]. Public and Global Health; 2020 Apr [cited 2020 May 28]. ' 'Available from: ' 'http://medrxiv.org/lookup/doi/10.1101/2020.04.12.20059618', 'DOI': '10.1101/2020.04.12.20059618'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.50', 'doi-asserted-by': 'publisher', 'DOI': '10.15585/mmwr.mm6912e3'}, { 'key': '2021012000000899000_2020.07.21.20159301v1.51', 'unstructured': 'Liu Y , Ning Z , Chen Y , Guo M , Liu Y , Gali NK , et al. Aerodynamic ' 'analysis of SARS-CoV-2 in two Wuhan hospitals. Nature [Internet]. 2020 ' 'Apr 27 [cited 2020 May 28]; Available from: ' 'http://www.nature.com/articles/s41586-020-2271-3'}], 'container-title': [], 'original-title': [], 'link': [ { 'URL': 'https://syndication.highwire.org/content/doi/10.1101/2020.07.21.20159301', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2021, 1, 20]], 'date-time': '2021-01-20T08:01:24Z', 'timestamp': 1611129684000}, 'score': 1, 'resource': {'primary': {'URL': 'http://medrxiv.org/lookup/doi/10.1101/2020.07.21.20159301'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2020, 7, 24]]}, 'references-count': 51, 'URL': 'http://dx.doi.org/10.1101/2020.07.21.20159301', 'relation': {}, 'published': {'date-parts': [[2020, 7, 24]]}, 'subtype': 'preprint'}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit