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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 20% Improvement Relative Risk Outpatient use 88% c19hcq.org Guisado-Vasco et al. HCQ for COVID-19 LATE TREATMENT Favors HCQ Favors control
Clinical characteristics and outcomes among hospitalized adults with severe COVID-19 admitted to a tertiary medical center and receiving antiviral, antimalarials, glucocorticoids, or immunomodulation with tocilizumab or cyclosporine: A retrospective observational study (COQUIMA cohort)
Guisado-Vasco
15 Oct 2020    Source   PDF   Share   Tweet
Retrospective 607 patients reporting results for early outpatient HCQ use with mortality odds ratio OR 0.092 [0.022-0.381], p = 0.001 (65 patients), and for hospital use, mortality odds ratio OR 0.737 [0.38-1.41], p = 0.36 (558 patients). Median age 69.
risk of death, 20.3% lower, RR 0.80, p = 0.36, treatment 127 of 558 (22.8%), control 14 of 49 (28.6%), NNT 17, adjusted per study, odds ratio converted to relative risk.
outpatient use, 88.0% lower, RR 0.12, p = 0.001, treatment 2 of 65 (3.1%), control 139 of 542 (25.6%), NNT 4.4, adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Guisado-Vasco et al., 15 Oct 2020, retrospective, Spain, peer-reviewed, median age 69.0, 25 authors.
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This PaperHCQAll
Late treatment
is less effective
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