Retrospective study focused on eosinophil recovery with 9,644 hospitalized patients in Spain, showing lower mortality for HCQ (14.7% vs 29.2%, p
<0.001), and AZ (15.3% vs. 18.4%, p
<0.001). With a multivariate model including potential confounding factors, HCQ and AZ are associated with lower mortality, HCQ OR 0.662, p
Although the 27% lower mortality is not statistically significant, it is consistent with the significant 22% lower mortality [18‑27%]
from meta analysis of the 232 mortality results to date
Gonzalez et al., 21 Aug 2020, retrospective, database analysis, Spain, preprint, 25 authors.