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Seroprevalence of COVID-19 Amongst Health Care Workers in a Tertiary Care Hospital of a Metropolitan City from India

Goenka et al., SSRN, doi:10.2139/ssrn.3689618
Oct 2020  
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IgG positive 87% Improvement Relative Risk HCQ for COVID-19  Goenka et al.  Prophylaxis Is pre-exposure prophylaxis with HCQ beneficial for COVID-19? Retrospective 962 patients in India Lower IgG positivity with HCQ (p=0.032) Goenka et al., SSRN, October 2020 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
*, now with p < 0.00000000001 from 411 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 75 treatments.
Study of SARS-CoV-2-IgG antibodies in 1122 health care workers in India finding 87% lower positives for adequate HCQ prophylaxis, 1.3% HCQ versus 12.3% for no HCQ prophylaxis.
Adequate prophylaxis is defined as 400mg 1/wk for >6 weeks.
risk of IgG positive, 87.2% lower, RR 0.13, p = 0.03, treatment 1 of 77 (1.3%), control 115 of 885 (13.0%), NNT 8.6, adjusted per study, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Goenka et al., 24 Oct 2020, retrospective, India, preprint, 11 authors.
This PaperHCQAll
Seroprevalence of COVID-19 amongst health care workers in a tertiary care hospital of a metropolitan city from India
Mahesh Kumar, Goenka Dm, MD Shivaraj Afzalpurkar, MSc Mohuya Mukherjee, MD Surabhi Jajodia, Bhavik Bharat, Consultant, Shah Dnb, MD Ujjwayini Khan, MD Syamasis Bandyopadhyay, Dr Mahesh Kumar Goenka
Seroprevalence of COVID-19 amongst health care workers in a tertiary care hospital of a metropolitan city from India
Supplementary material Questionnaire for the study population This preprint research paper has not been peer reviewed. Electronic copy available at: P r e p r i n t n o t p e e r r e v i e w e d
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