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Is vitamin D level important in pregnant women with COVID-19?

Değirmenci et al., Journal of Controversies in Obstetrics & Gynecology and Pediatrics, doi:10.51271/JCOGP-0035
Jul 2024  
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Hospitalization 43% Improvement Relative Risk HCQ for COVID-19  Değirmenci et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 125 patients in Turkey (March 2020 - January 2021) No significant difference in hospitalization c19hcq.org Değirmenci et al., J. Controversies in.., Jul 2024 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020, now with p < 0.00000000001 from 419 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19hcq.org
Retrospective 125 pregnant women hospitalized with COVID-19 in Turkey, showing no significant difference in hospitalization length with HCQ, and longer hospitalization with lopinavir/ritonavir use.
Study covers HCQ and vitamin D.
risk of hospitalization, 42.8% lower, OR 0.57, p = 0.76, treatment 10, control 115, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Değirmenci et al., 30 Jul 2024, retrospective, Turkey, peer-reviewed, mean age 29.3, 7 authors, study period March 2020 - January 2021. Contact: mulayimsizer@hotmail.com.
This PaperHCQAll
{ 'indexed': {'date-parts': [[2024, 8, 9]], 'date-time': '2024-08-09T00:10:17Z', 'timestamp': 1723162217242}, 'reference-count': 0, 'publisher': 'MediHealth Academy', 'issue': '3', 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'abstract': '<jats:p>Aims: The Covid-19 pandemic started in Wuhan City, Hubei Province, China in late ' 'December 2019. In our study, we aimed to evaluate the effectiveness of vitamin D levels on ' 'the clinic of the disease, laboratory findings, severity of the disease and, length of ' 'hospital stay by grouping pregnant patients with a diagnosis of Covid-19 according to their ' 'vitamin D levels.\n' 'Methods: A total of 125 patients were included. According to the vitamin D levels of the ' 'patients at the time of hospitalization, two groups were determined as below and above ' '20ng/ml, which is the limit of vitamin D deficiency. The patients in these two groups were ' 'compared in terms of demographic features, clinical findings, laboratory findings, imaging ' 'findings, hospitalization times and need for intensive care.\n' 'Results: When evaluated according to serum 25 hydroxyvitamin D level, patients’ fever, pulse, ' 'oxygen saturation, the severity of lung involvement in computed tomography, hospitalization ' 'there was no statistically significant difference between the groups in terms of duration and ' 'need for intensive care. When the laboratory parameters of the patients at hospitalization ' 'were compared according to serum 25 hydroxyvitamin D levels, there was no statistically ' 'significant difference between the two groups in terms of any laboratory parameter. As a ' 'result of the analysis, only lymphocyte count was determined as the independent variable ' 'affecting the severity of lung involvement in thorax CT (Computed tomography). As the ' 'lymphocyte count decreased, the severity of involvement in thorax CT increased.\n' 'Conclusion: Our study showed that vitamin D level did not have a significant relationship ' 'with any of the parameters related to Covid-19 such as clinical and laboratory findings, ' 'severity of the disease and duration of hospitalisation. It is also supported by our study ' 'that the decrease in lymphocyte counts is associated with severe Covid-19 disease.</jats:p>', 'DOI': '10.51271/jcogp-0035', 'type': 'journal-article', 'created': {'date-parts': [[2024, 8, 8]], 'date-time': '2024-08-08T06:06:54Z', 'timestamp': 1723097214000}, 'page': '51-57', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Is vitamin D level important in pregnant women with COVID-19?', 'prefix': '10.51271', 'volume': '2', 'author': [ { 'ORCID': 'http://orcid.org/0000-0003-4685-3335', 'authenticated-orcid': False, 'given': 'Ahmet', 'family': 'Değirmenci', 'sequence': 'first', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0002-9306-6281', 'authenticated-orcid': False, 'given': 'Sertaç', 'family': 'Ayçiçek', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0001-9142-6127', 'authenticated-orcid': False, 'given': 'Fatih Mehmet', 'family': 'Fındık', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-4864-7287', 'authenticated-orcid': False, 'given': 'Mulaim', 'family': 'Sizer', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0009-0006-1602-4009', 'authenticated-orcid': False, 'given': 'Azize Pervin', 'family': 'Değirmenci', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-0108-2856', 'authenticated-orcid': False, 'given': 'Pelin', 'family': 'Değirmenci Ayçiçek', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-1836-6281', 'authenticated-orcid': False, 'given': 'Çiğdem', 'family': 'Mermutluoğlu', 'sequence': 'additional', 'affiliation': []}], 'member': '28304', 'published-online': {'date-parts': [[2024, 7, 30]]}, 'container-title': 'Journal of Controversies in Obstetrics &amp; Gynecology and Pediatrics', 'original-title': [], 'deposited': { 'date-parts': [[2024, 8, 8]], 'date-time': '2024-08-08T06:06:57Z', 'timestamp': 1723097217000}, 'score': 1, 'resource': {'primary': {'URL': 'http://journal-jcogp.com/Publication/DisplayArticle/27358'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2024, 7, 30]]}, 'references-count': 0, 'journal-issue': {'issue': '3', 'published-online': {'date-parts': [[2024, 7, 30]]}}, 'URL': 'http://dx.doi.org/10.51271/JCOGP-0035', 'relation': {}, 'ISSN': ['2980-0579'], 'subject': [], 'container-title-short': 'JCOGP', 'published': {'date-parts': [[2024, 7, 30]]}}
Late treatment
is less effective
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