Abstract: tio cina n ac Journal o OPEN ne acci s & V fV ISSN: 2157-7560 Journal of Vaccines & Vaccination ACCESS Freely available online Short Communication No Role of HCQ in COVID-19 Prophylaxis: A Survey amongst Indian Doctors Debasis Datta 1, Samit Ghosal2*, Binayak Sinha3, Sujata Datta4,Twisha Chakraborty5, Kalyan Kumar Gangopadhyay6, Arup Ratan Dutta7 Department of Gastroenterology, Fortis Hospitals, Kolkata, India; 2Department of Endocrinology, Nightingale Hospital, Kolkata, India;3Department of Diabetes and Endocrinology, AMRI Hospitals, Kolkata, India;4Department of Gynecology, Peerless Hospitals, Kolkata, India;5 Department of Gastroenterology, Fortis Hospitals Kolkata, India;6 Department of Endocrinology, Peerless Hospitals, Kolkata, India;7Department of Nephrology, Fortis Hospitals, Kolkata, India 1 ABSTRACT The COVID-19 pandemic is being tackled on two fronts-prevention and treatment. In addition to behavioural strategies and vaccines (eagerly awaited), pharmacotherapy is also being employed in certain regions as a preventive strategy. In India, hydroxychloroquine (HCQ), ivermectin, a variety of vitamin supplements are being used, with HCQ being the most popular among healthcare professionals. In addition to the evidence-based recommendations, it is important to ascertain the situation on the ground. We conducted a multicentric survey among physicians from a wide range of specialities to ascertain the usage on HCQ and its effects of COVID-19 prevention. We did not find any significant impact of HCQ on the prevention of COVID-19 (p=0.54) independent of the duration of its usage. This pilot project has the potential to act as a backbone for a larger study exploring the impact of pharmacological intervention on COVID-19 prevention. Keywords: COVID-19; Survey; Physicians; HCQ