Clinical characteristics and outcomes of COVID-19 patients in a tertiary hospital in Baguio City, Philippines
Cortez et al.,
Clinical characteristics and outcomes of COVID-19 patients in a tertiary hospital in Baguio City, Philippines,
Western Pacific Surveillance and Response Journal, doi:10.5365/wpsar.2021.12.4.852
Retrospective 280 hospitalized patients in the Philippines, 25 treated with HCQ, not showing any significant differences in unadjusted results.
Although the 15% lower mortality is not statistically significant, it is consistent with the significant 22% lower mortality
[18‑27%] from meta analysis of the
232 mortality results to date.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details.
risk of death, 15.0% lower, RR 0.85, p = 1.00, treatment 1 of 25 (4.0%), control 12 of 255 (4.7%), NNT 142.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Cortez et al., 11 Nov 2021, retrospective, Philippines, peer-reviewed, 29 authors, study period March 2020 - October 2020.
Abstract: COVID-19: Original Research
Clinical characteristics and outcomes of
COVID-19 patients in a tertiary hospital in
Baguio City, Philippines
Karen Joyce C. Cortez,a Bernard A. Demot,a Samantha S. Bartolo,a Dexter D. Feliciano,a Verna Moila P. Ciriaco,a Imari Irish E.
Labi,a Denzelle Diane M. Viray,a Jenna Charise M. Casuga,a Karol Anne B. Camonayan-Flor,a Precious Mae A. Gomez,a Marie
Ellaine N. Velasquez,a Thea Pamela T. Cajulao,a Jovy E. Nigos,a Maria Lowella F. De Leon,a Domingo P. Solimen,a Angelita G.
Go,a Francis M. Pizarro,a Larry C. Haya Jr,a Ray P. Aswat,a Virginia B. Mangati,a Caesar Noel I. Palaganas,a Mylene N. Genuino,a
Kimberley M. Cutiyog-Ubando,a Karen C. Tadeo,a Marienelle L. Longid,a Nowell Benedict C. Catbagan,a Joel B. Bongotan,a
Beverly Anne T. Dominguez-Villara and Joeffrey B. Dalaoa
Correspondence to Karen Joyce C. Cortez (email: medicine@bghmc.doh.gov.ph)
Objective: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), primarily targets the respiratory system. This study describes the characteristics associated with mortality
among patients infected with SARS-CoV-2 at a single hospital in Baguio City, Philippines.
Methods: We reviewed medical records (including history, laboratory results and treatment regimen) of 280 confirmed
COVID-19 patients admitted to a single hospital during March–October 2020. Clinical characteristics and outcomes
(frequency and type of complication, recovery rate and mortality) were evaluated. Multiple logistic regression was used to
analyse factors associated with mortality.
Results: The mean age of COVID-19 patients was 48.4 years and the female-to-male ratio was 1.8:1. Hypertension,
cardiovascular disease (CVD) and diabetes were the most frequent comorbidities reported. Common presenting symptoms
were respiratory and constitutional, with 41% of patients not reporting symptoms on admission. Patients with moderate,
severe and critical disease comprised 45%, 8% and 4%, respectively. A total of 15% had complications, health careassociated pneumonia being the most frequent complication. The recovery rate was 95%; 5% of patients died, with
multiorgan failure being the most common cause. The presence of CVD, chronic kidney disease, prolonged prothrombin
time and elevated lactate dehydrogenase (LDH) were associated with mortality.
Discussion: Most COVID-19 patients in our population had asymptomatic to moderate disease on admission. Mortality
from COVID-19 was associated with having CVD, chronic kidney disease, elevated LDH and prolonged prothrombin
time. Based on these results, we emphasize that people should take all necessary precautions to avoid infection with
SARS-CoV-2.
C
oronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), primarily targets the respiratory
system. In December 2019, an epidemiological alert was
released in China following a rise in cases of pneumonia
of unknown cause. The Philippines announced its first
confirmed case on 31 January 2020.1,2 The World
Health Organization (WHO) officially declared a global
pandemic on 11 March 2020, by which time the
Philippines already had 49 confirmed cases, largely in
the National Capital Region.2
Baguio City is located north of Manila, within the
Cordillera Central mountain range in northern Luzon.
The estimated population is 345 000, with adults (aged
19–60 years) and those aged over 60 years comprising
52% and 6.6% of the..
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