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0 0.5 1 1.5 2+ Mortality -399% Improvement Relative Risk c19hcq.org Çivriz Bozdağ et al. HCQ for COVID-19 LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 175 patients in Turkey Higher mortality with HCQ (p=0.003) Çivriz Bozdağ et al., Turk. J. Haematol., doi:10.4274/tjh.galenos.2021.2021.0287 Favors HCQ Favors control
Clinical Characteristics and Outcome of COVID-19 in Turkish Hematological Malignancy Patients
Çivriz Bozdağ et al., Turk. J. Haematol., doi:10.4274/tjh.galenos.2021.2021.0287
Çivriz Bozdağ et al., Clinical Characteristics and Outcome of COVID-19 in Turkish Hematological Malignancy Patients, Turk. J. Haematol., doi:10.4274/tjh.galenos.2021.2021.0287
Sep 2021   Source   PDF  
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Retrospective 340 patients with hematological malignancy in Turkey, showing higher mortality with HCQ treatment. Confounding by time is likely because more HCQ patients were earlier in time when overall treatment protocols were significantly worse. This study is excluded in the after exclusion results of meta analysis: substantial confounding by time likely due to declining usage over the early stages of the pandemic when overall treatment protocols improved dramatically.
risk of death, 399.2% higher, RR 4.99, p = 0.003, treatment 35, control 140.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Çivriz Bozdağ et al., 15 Sep 2021, retrospective, Turkey, peer-reviewed, 62 authors.
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Abstract: ResearchTJH-2021-0287.R2 doi: 10.4274/tjh.galenos.2021.2021.0287 pr oo f Clinical Characteristics and Outcome of COVID-19 in Turkish Hematological Malignancy Patients Çivriz Bozdağ S. et al: OVID-19 in Hematological Malignancies 1 rre ct ed Sinem Çivriz Bozdağ1, Güldane Cengiz Seval2, İpek Yonal-Hindilerden3, Fehmi Hindilerden4, Neslihan Andıç5, Mustafa Baydar6, Lale Aydın Kaynar7, Selami Toprak8, Hasan Göksoy9, Berrin Balık10, Ufuk Demirci11, Ferda Can12, Vildan Özkocaman13, Eren Gündüz14, Tuğba Zeynep Güven15, Zübeyde Nur Özkurt16, Sinan Demircioğlu17, Meral Beksaç18, İdris İnce19, Umut Yılmaz20, Hilal Eroğlu Küçükdiler21, Elgün Abishov22, Boran Yavuz23, Ünal Ataş24, Yaşa Gül Mutlu25, Volkan Bas26, Hava Üsküdar Teke27, Vildan Gürsoy28, Serhat Çelik29, Rafiye Çiftçiler30, Münci Yagcı31, Pervin Topçuoğlu32, Özcan Çeneli33, Hamza Abbasov34, Cem Selim35, Muhlis Cem Ar36, Kemal Orhan Yüce37, Sevil Sadri38, Canan Albayrak39, Nil Güler40, Muzaffer Keklik41, Hatice Terzi42, Ali Doğan43, Arzu Zeynep Yegin44, Meltem Kurt Yüksel45, Sadri Sogol46, İrfan Yavaşoğlu47, Hüseyin Beköz48, Tekin Aksu49, Senem Maral50, Veysel Erol51, Leylagül Kaynar52, Osman İlhan53, Ali Zahit Bolaman54, Gökmen Ömür Sevindik55, Arzu Akyay56, Muhit Özcan57, Günhan Gürman58, Şule Ünal59, Yasemin Yavuz60, Reyhan Diz Küçükkaya61, Güner Hayri Özsan62 Ankara University, Ankara, Turkey Ankara University Faculty of Medicine, Department of Hematology, Ankara, Turkey 3 İstanbul University Faculty of Medicine, Department of Internal Medicine, İstanbul, Turkey 4 University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Hematology, İstanbul, Turkey 5 Osmangazi University Faculty of Medicine, Department of Hematology, Eskişehir, Turkey 6 Erciyes University Faculty of Medicine, Kayseri, Turkey 7 Gazi University Faculty of Medicine, Department of Hematology, Ankara, Turkey 8 Ankara University School of Medicine, Ankara, Turkey 9 Yeni Yüzyıl University Özel Gaziosmanpaşa Hospital, Division of Haematology, Department of Internal Medicine, İstanbul, Turkey 10 Medipol Mega Hospital, Turkey 11 Trakya University, Edirne, Turkey 12 Ministry of Health Ankara City Hospital, Ankara, Turkey 13 Uludağ University School of Medicine, Division of Hematology, Department of Internal Medicine, Bursa, Turkey 14 Eskisehir Osmangazi University School of Medicine Department of Hematology, Eskişehir, Turkey 15 Erciyes University, Kayseri, Turkey un co 2 16 Gazi University Department of Hematology, Ankara, Turkey Necmettin Erbakan University, Meram School of Medicine, Hematology Meram School of Medicine, Konya, Turkey 18 Ankara University Faculty of Medicine, Ankara, Turkey 19 Dr Ersin Arslan Training and Research Hospital, Gaziantep, Turkey 20 Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine - Department of Internal Medicine, Division of Hematology 21 Adnan Menderes University, Department of Hematology, Aydın, Turkey 22 Yeni Yüzyıl University, Özel Gaziosmanpaşa Hospital, Istanbul, Turkey 23 Dokuz Eylül University, İzmir, Turkey 24 Akdeniz University, Antalya, Turkey 25 İstanbul Medipol University, Department of Hematology, İstanbul, Turkey 26 Trakya University Faculty of Medicine, Department of Hematology, Edirne, Turkey 27 Uludağ University Faculty of Medicine, Department of Internal medicine, Bursa, Turkey 28 Eskişehir Osmangazi University Faculty of Medicine, Department of Hematology, Eskişehir, Turkey 29 Bursa, Turkey 30 Erciyes..
Late treatment
is less effective
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