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Clinical characteristics and factors associated with ICU mortality during the first year of the SARS-Cov-2 pandemic in Romania

Bubenek-Turconi et al., European Journal of Anaesthesiology, doi:10.1097/EJA.0000000000001776
Nov 2022  
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Mortality 22% Improvement Relative Risk HCQ for COVID-19  Bubenek-Turconi et al.  ICU PATIENTS Is very late treatment with HCQ beneficial for COVID-19? Prospective study in Romania (March 2020 - March 2021) Lower mortality with HCQ (p=0.014) c19hcq.org Bubenek-Turconi et al., European J. An.., Nov 2022 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020, now with p < 0.00000000001 from 419 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 109 treatments. c19hcq.org
Prospective study of 9,058 COVID-19 ICU patients in Romania, showing lower mortality with HCQ treatment.
risk of death, 22.0% lower, OR 0.78, p = 0.01, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Bubenek-Turconi et al., 17 Nov 2022, prospective, Romania, peer-reviewed, 16 authors, study period March 2020 - March 2021.
This PaperHCQAll
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Late treatment
is less effective
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