Clinical characteristics, frailty and mortality of residents with COVID-19 in nursing homes of a region of Madrid
et al., Journal of the American Medical Directors Association,
Retrospective 630 elderly patients in Spain showing lower mortality with HCQ treatment, unadjusted relative risk RR 0.78, p
= 0.09. HCQ was used more often with patients that were hospitalized (24% versus 3% use in the nursing homes). Median age 87.
Although the 22% lower mortality is not statistically significant, it is consistent with the significant 22% lower mortality [18‑27%]
from meta analysis of the 228 mortality results to date
risk of death, 21.5% lower, RR 0.78, p = 0.09, treatment 33 of 91 (36.3%), control 249 of 539 (46.2%), NNT 10.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta
unadjusted results with no group details.
Bielza et al., 11 Dec 2020, retrospective, Spain, peer-reviewed, median age 87.0, 24 authors.