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SARS-CoV-2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms

Sofian et al., Wiener Medizinische Wochenschrift, doi:10.1007/s10354-020-00793-8
Dec 2020  
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HCQ for COVID-19
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Report on a series of 10 patients experiencing prolonged COVID-19 symptoms that were given HCQ 250mg bid for 5 days, with resolution of symptoms in all cases, and patients reporting they felt much better 2 days after treatment initiation.
Sofian et al., 14 Dec 2020, peer-reviewed, 7 authors.
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SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
Masoomeh Sofian, Ali Akbar Velayati, Mohammad Banifazl, Fatemeh Fotouhi, PhD Mona Sadat Larijani, Neda Afzali, MD Amitis Ramezani
Wiener Medizinische Wochenschrift, doi:10.1007/s10354-020-00793-8
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the causative agent of the ongoing pandemic, has spread into more than 200 countries to date. The disease which is caused by the virus is termed COVID-19. In most cases, it presents at first like common flu with cough and other respiratory symptoms. Nevertheless, other symptoms have been reported, such as a feeling of extreme fatigue, gastrointestinal symptoms, or acute onset of olfactory and gustatory dysfunction. Here we report a series of 10 cases (1 male, 9 females) observed between February and April 2020, with an undulating appearance and disappearance of symptoms. Weeks passed before the diagnosis was established. Symptoms resolved rapidly after treatment with hydroxy-
Conflict of interest M. Sofian, A.A. Velayati, M. Banifazl, F. Fotouhi, M.S. Larijani, N. Afzali, and A. Ramezani declare that they have no competing interests. Ethical standards The study design was approved by the Arak University of Medical Sciences Ethical Committee (IR.ARAKMU.REC.1399.002). Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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Late treatment
is less effective
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