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COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched Analysis of Cicatricial Alopecia Patients

Shaw et al., Journal of Drugs in Dermatology, doi:10.36849/JDD.5843
Jul 2021  
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Case 13% Improvement Relative Risk HCQ for COVID-19  Shaw et al.  Prophylaxis Is pre-exposure prophylaxis with HCQ beneficial for COVID-19? PSM retrospective 144 patients in the USA (March - May 2020) Fewer cases with HCQ (p=0.006) c19hcq.org Shaw et al., J. Drugs in Dermatology, Jul 2021 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020, now with p < 0.00000000001 from 419 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19hcq.org
PSM retrospective 144 alopecia patients in the USA, showing lower risk of COVID-19 with HCQ prophylaxis. The supplemental appendix is not available.
risk of case, 13.0% lower, OR 0.87, p = 0.006, treatment 45, control 99, adjusted per study, propensity score matching, multivariable, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Shaw et al., 1 Jul 2021, retrospective, USA, peer-reviewed, 10 authors, study period 1 March, 2020 - 15 May, 2020. Contact: Kristen.LoSicco@nyulangone.org.
This PaperHCQAll
Abstract: doi:10.36849/JDD.5843 To order reprints or e-prints of JDD articles please contact sales@jddonline.com August 2021 914 Volume 20 • Issue 8 Copyright © 2021 LETTERS TO THE EDITOR Journal of Drugs in Dermatology COVID-19 in Individuals Treated With Long-Term Hydroxychloroquine: A Propensity Score-Matched Analysis of Cicatricial Alopecia Patients Katharina S. Shaw,a Lu Yin,a Jinal K. Shah,b Rachel A. Sally,a Katerina S. Svigos,a Prince U. Adotama,a Hsiao Han Tuan,a Jerry Shapiro MD,a Rebecca A. Betensky,b* and Kristen I. Lo Sicco MDa* The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY b Department of Biostatistics, New York University School of Global Public Health, New York, NY a Both authors contributed equally to this work as co-first authors *
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