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Incidence of arrhythmias and electrocardiographic abnormalities in symptomatic pediatric patients with PCR positive SARS-CoV-2 infection including drug induced changes in the corrected QT interval (QTc)

Samuel et al., Heart Rhythm, doi:10.1016/j.hrthm.2020.06.033
Jul 2020  
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In pediatric patients with PCR positive active COVID-19 infection, significant arrhythmias are infrequent, but occur at an incidence higher than expected in a general pediatric population. Comorbidities are not more common in patients with arrhythmias than in patients without arrhythmias. However, providers still need to be vigilant for comorbidities that may independently place patients at risk for arrhythmias. COVID-19 treatment using HCQ leads to significant QTc prolongation, but was not associated with arrhythmias in pediatric patients. The long term sequelae of arrhythmia development in this population and their impact on outcome needs to be studied.
Samuel et al., 1 Jul 2020, peer-reviewed, 7 authors.
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Incidence of arrhythmias and electrocardiographic abnormalities in symptomatic pediatric patients with PCR-positive SARS-CoV-2 infection, including drug-induced changes in the corrected QT interval
MD. Sharmeen Samuel, MD Richard A Friedman, MD Chetan Sharma, MD Madhusudan Ganigara, MD Elizabeth Mitchell, MD Charles Schleien, MD. Andrew D Blaufox
Heart Rhythm, doi:10.1016/j.hrthm.2020.06.033
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
References
Aghagoli, Marin, Soliman, Sellke, Cardiac involvement in COVID-19 patients: Risk factors, predictors, and complications: A review, Journal of Cardiac Surgery
Basu-Ray, Almaddah N K, Adeboye, Soos, Cardiac Manifestations Of Coronavirus (COVID-19)
Bessière, Roccia, Delinière, Assessment of QT Intervals in a Case Series of Patients With Coronavirus Disease 2019 (COVID-19) Infection Treated With Hydroxychloroquine Alone or in Combination With Azithromycin in an Intensive Care Unit, JAMA Cardiol
Borba, Val, Sampaio, Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial, JAMA Netw Open American Medical Association
Chen, Hu, Zhang, Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial
Chorin, Dai, Shulman, The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin
Crosson, Callans, Bradley, PACES/HRS Expert Consensus Statement on the Evaluation and Management of Ventricular Arrhythmias in the Child With a Structurally Normal Heart, Heart Rhythm
Cucinotta, Vanelli, WHO Declares COVID-19 a Pandemic, Acta Biomed
Davignon, Rautaharju, Boisselle, Normal ECG Standards for Infants and CHildren, Pediatr Cardiol
Fauchier, Fauchier, Babuty, Breuillac, Cosnay et al., Drug-induced ventricular tachycardia, Arch Mal Coeur Vaiss
Giudicessi, Noseworthy, Friedman, Ackerman, Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19), Mayo Clinic Proceedings
Guo, Fan, Chen, Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19), JAMA Cardiol, doi:10.1001/jamacardio.2020.1017
Kupferschmidt, Cohen, Race to find COVID-19 treatments accelerates, Science American Association for the Advancement of Science
Lakkireddy, Chung, Gopinathannair, Guidance for Cardiac Electrophysiology During the Coronavirus (COVID-19) Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association, Heart Rhythm
Rautaharju, Surawicz, Gettes, AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology, J Am Coll Cardiol
Rosenberg, Dufort, Udo, Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State, JAMA
Stephanie, Coromilas Ellie, Ani, Cardiac Arrhythmias in COVID-19
Verdoni, Mazza, Gervasoni, An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study, The Lancet
Wang, Hu, Hu, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China, JAMA American Medical Association
Zhou, Yu, Du, Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study, Lancet
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