Effectiveness of Prophylactic Hydroxychloroquine on incidence of COVID-19 infection in Front-line Health and Allied Health Care Workers: The COVID-SHIELD Trial

Pellegrini et al., COVID-SHIELD, ACTRN12620000501943, COVID-SHIELD, ACTRN12620000501943

Sep 2020

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Estimated 2,250 participant HCQ prophylaxis RCT with results not reported over 3 years after estimated completion.

The lead investigators are Prof. Marc Pellegrini and Prof. Ian Wicks centenary.org.au, findanexpert.unimelb.edu.au, viin.org.au, wehi.edu.au. For more information see anzctr.org.au, twitter.com, web.archive.org, wehi.edu.au (B).

38 HCQ RCTs have results missing long after expected Abu-Helalah, Ajili, Akram, Al Ansari, Aston, Borrie, Burney, Butler, Chauffe, Connor, El-Sherbiny, Farooq, Gagneux-Brunon, Genton, Ghanem-Zoubi, González, Granados-Montiel, Gül, Hawari, James, Kara, Kim, Levi, Mežnar, Moraes, Morales-Asencio, Mordmüller, Nanni, Niriella, Okasha, Pellegrini, Pineda, Sarwar, Sarwar (B), Sow, Treluyer, WellStar, White
The trials report a total of 25,149 patients, with 13 trials having actual enrollment of 8,689, and the remainder estimated.

1. anzctr.org.au, www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379618&isReview=true.www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379618&isReview=true.

2. centenary.org.au, www.centenary.org.au/people/professor-marc-pellegrini/.www.centenary.org.au/people/professor-marc-pellegrini/.

3. findanexpert.unimelb.edu.au, findanexpert.unimelb.edu.au/profile/4135-marc-pellegrini.findanexpert.unimelb.edu.au/profile/4135-marc-pellegrini.

4. twitter.com, twitter.com/Jikkyleaks/status/1690565786836877312.twitter.com/Jikkyleaks/status/1690565786836877312.

5. viin.org.au, viin.org.au/member/marc-pellegrini.viin.org.au/member/marc-pellegrini.

6. web.archive.org, web.archive.org/web/20200604212226/https://www.covidshieldtrial.com.au/#!/.web.archive.org/web/20200604212226/https://www.covidshieldtrial.com.au/#!/.

7. wehi.edu.au, www.wehi.edu.au/researcher/ian-wicks/.www.wehi.edu.au/researcher/ian-wicks/.

8. wehi.edu.au (B), www.wehi.edu.au/news/covid19-prevention-trial-opens-high-risk-healthcare-workers/.www.wehi.edu.au/news/covid19-prevention-trial-opens-high-risk-healthcare-workers/.

Important missing comments or errors? Let us know.

Pellegrini et al., 12 Sep 2020, Double Blind Randomized Controlled Trial, placebo-controlled, trial ACTRN12620000501943 (COVID-SHIELD).

Contact: communityrelations@wehi.edu.au, wicks@wehi.edu.au, mpell@unimelb.edu.au, pellegrini@wehi.edu.au.

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