Retrospective 766 hospitalized patients in DRC showing mortality reduced from 29% to 11%, and improvement at 30 days increased from 65% to 84%.
Mortality cox regression adjusted hazard ratio aHR 0.26, p
Risk of no improvement adjusted odds ratio aOR 0.28, p
Using marginal structural model analysis these risks became:
Mortality MSM adjusted odds ratio aOR 0.65, p
Risk of no improvement MSM adjusted odds ratio aOR = 0.65, p
Median age 46, 630 treated with CQ+AZ.
Although the 28% lower mortality is not statistically significant, it is consistent with the significant 25% lower mortality [20‑29%]
from meta analysis of the 247 mortality results to date
Nachega et al., 2 Oct 2020, retrospective, database analysis, DR Congo, peer-reviewed, median age 46.0, 25 authors.