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All Studies   Meta Analysis    Recent:   

Comparison of Lopinavir/​Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19)

Kim et al., NCT04307693, NCT04307693
Apr 2020  
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HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now with p < 0.00000000001 from 411 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 79 treatments. c19hcq.org
65 patient HCQ early treatment RCT with results not reported over 4 years after completion. This trial was terminated early but should still report results. While the trial may be underpowered when considered alone, results still contribute to the overall body of evidence and to meta analysis results. Patients also risked their life to participate.
38 HCQ RCTs have results missing long after expected1-38
The trials report a total of 25,399 patients, with 12 trials having actual enrollment of 8,139, and the remainder estimated.
Kim et al., 30 Apr 2020, Randomized Controlled Trial, trial NCT04307693 (history). Contact: shkimmd@amc.seoul.kr.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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